Results 61 to 70 of about 3,661,970 (379)

Comparative efficacy of Chinese herbal injections for treating chronic heart failure: a network meta-analysis

open access: yesBMC Complementary and Alternative Medicine, 2018
Background On account of deterioration of chronic heart failure (CHF) and extensive exploration of Chinese herbal injections (CHIs), we performed a network meta-analysis to investigate the efficacy of CHIs (Huangqi injection, Shenfu injection, Shengmai ...
Kai-Huan Wang   +4 more
doaj   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Precision medicine and molecular imaging: new targeted approaches toward cancer therapeutic and diagnosis [PDF]

open access: yes, 2016
: This paper presents a review of the importance and role of precision medicine and molecular imaging technologies in cancer diagnosis with therapeutics and diagnostics purposes.
Alipour, Zeinab   +4 more
core   +1 more source

Identification and characterization of the Cucurbitacins, a novel class of small-molecule inhibitors of Tropomyosin receptor kinase a

open access: yesBMC Complementary and Alternative Medicine, 2019
Background NGF-TrkA is well known to play a key role in propagating and sustaining pruritogenic signals, which form the pathology of chronic pruritus. Inhibition of NGF-TrkA is a known strategy for the treatment of pruritus.
Yueling Zhong   +9 more
doaj   +1 more source

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

Epigenomes in Cardiovascular Disease. [PDF]

open access: yes, 2018
If unifying principles could be revealed for how the same genome encodes different eukaryotic cells and for how genetic variability and environmental input are integrated to impact cardiovascular health, grand challenges in basic cell biology and ...
McKinsey TA   +4 more
core   +1 more source

Chebulinic acid derived from triphala is a promising antitumour agent in human colorectal carcinoma cell lines

open access: yesBMC Complementary and Alternative Medicine, 2018
Background Triphala is an Ayurvedic rasayana formulation reputed for its antitumour activities, and chebulinic acid and chebulagic acid, along with other phenolic acids, have been proposed to be responsible for its effects.
Min Wang, Yanru Li, Xianda Hu
doaj   +1 more source

Responding to COVID-19: The UW Medicine Information Technology Services Experience

open access: yesApplied Clinical Informatics, 2020
Background UW Medicine was one of the first health systems to encounter and treat COVID-19 patients in the United States, starting in late February 2020.
Elisha S. Grange   +11 more
semanticscholar   +1 more source

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

open access: yesFEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

Discussion on Etiology and Pathogenesis of Corona Virus Disease 2019 from “Cold-dampness and Insidious Dryness”

open access: yesDigital Chinese Medicine, 2020
Based on the characteristics of the epidemic situation and the authors’ understanding of the related ancient books and documents, this paper explores the etiology and pathogenesis of Corona Virus Disease 2019 (COVID-19) from 5 aspects: abnormal climate ...
Lu Fang-Guo   +4 more
doaj  

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