Results 61 to 70 of about 3,661,970 (379)
Background On account of deterioration of chronic heart failure (CHF) and extensive exploration of Chinese herbal injections (CHIs), we performed a network meta-analysis to investigate the efficacy of CHIs (Huangqi injection, Shenfu injection, Shengmai ...
Kai-Huan Wang+4 more
doaj +1 more source
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Precision medicine and molecular imaging: new targeted approaches toward cancer therapeutic and diagnosis [PDF]
: This paper presents a review of the importance and role of precision medicine and molecular imaging technologies in cancer diagnosis with therapeutics and diagnostics purposes.
Alipour, Zeinab+4 more
core +1 more source
Background NGF-TrkA is well known to play a key role in propagating and sustaining pruritogenic signals, which form the pathology of chronic pruritus. Inhibition of NGF-TrkA is a known strategy for the treatment of pruritus.
Yueling Zhong+9 more
doaj +1 more source
Social context prevents heat hormetic effects against mutagens during fish development
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere+5 more
wiley +1 more source
Epigenomes in Cardiovascular Disease. [PDF]
If unifying principles could be revealed for how the same genome encodes different eukaryotic cells and for how genetic variability and environmental input are integrated to impact cardiovascular health, grand challenges in basic cell biology and ...
McKinsey TA+4 more
core +1 more source
Background Triphala is an Ayurvedic rasayana formulation reputed for its antitumour activities, and chebulinic acid and chebulagic acid, along with other phenolic acids, have been proposed to be responsible for its effects.
Min Wang, Yanru Li, Xianda Hu
doaj +1 more source
Responding to COVID-19: The UW Medicine Information Technology Services Experience
Background UW Medicine was one of the first health systems to encounter and treat COVID-19 patients in the United States, starting in late February 2020.
Elisha S. Grange+11 more
semanticscholar +1 more source
Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley +1 more source
Based on the characteristics of the epidemic situation and the authors’ understanding of the related ancient books and documents, this paper explores the etiology and pathogenesis of Corona Virus Disease 2019 (COVID-19) from 5 aspects: abnormal climate ...
Lu Fang-Guo+4 more
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