Results 81 to 90 of about 6,287,948 (363)

Ontology as the core discipline of biomedical informatics: Legacies of the past and recommendations for the future direction of research [PDF]

open access: yes, 2007
The automatic integration of rapidly expanding information resources in the life sciences is one of the most challenging goals facing biomedical research today.
Ceusters, Werner, Smith, Barry
core  

Altering the inhibitory kinetics and molecular conformation of maltase by Tangzhiqing (TZQ), a natural α-glucosidase inhibitor

open access: yesBMC Complementary Medicine and Therapies, 2020
Background Tangzhiqing (TZQ), as a potential α-glycosidase inhibitor, possesses postprandial hypoglycaemic effects on maltose in humans. The aim of this study was to investigate the mechanisms by which TZQ attenuates postprandial glucose by interrupting ...
Yanfen Li   +8 more
doaj   +1 more source

Artificial intelligence in medicine: current trends and future possibilities.

open access: yesThe British journal of general practice : the journal of the Royal College of General Practitioners, 2018
Artificial intelligence (AI) research within medicine is growing rapidly. In 2016, healthcare AI projects attracted more investment than AI projects within any other sector of the global economy.1 However, among the excitement, there is equal scepticism,
V. Buch, Irfan Ahmed, M. Maruthappu
semanticscholar   +1 more source

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

Controlled surface initiated polymerization of N-isopropylacrylamide from polycaprolactone substrates for regulating cell attachment and detachment [PDF]

open access: yes, 2012
Poly(ε-caprolactone) (PCL) substrates were modified with thermoresponsive poly(N-isopropylacrylamide) (PNIPAM) brushes to direct and control cellular attachment and detachment. Prior to brush growth, the surface of PCL was activated by a diamine to allow
Blitterswijk, C.A. van   +5 more
core   +3 more sources

PAMs inhibits monoamine oxidase a activity and reduces glioma tumor growth, a potential adjuvant treatment for glioma

open access: yesBMC Complementary Medicine and Therapies, 2020
Background Monoamine oxidase (MAO) A catalyzes oxidative deamination of monoamine neurotransmitters and dietary amines and regulates brain development and functions.
Pei-Chuan Li   +5 more
doaj   +1 more source

Trends in Use of Medical Imaging in US Health Care Systems and in Ontario, Canada, 2000-2016.

open access: yesJournal of the American Medical Association (JAMA), 2019
Importance Medical imaging increased rapidly from 2000 to 2006, but trends in recent years have not been analyzed. Objective To evaluate recent trends in medical imaging.
R. Smith-Bindman   +14 more
semanticscholar   +1 more source

miRNA‐29 regulates epidermal and mesenchymal functions in skin repair

open access: yesFEBS Letters, EarlyView.
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan   +10 more
wiley   +1 more source

Analysis of microRNA expression in peripheral blood monocytes of three Traditional Chinese Medicine (TCM) syndrome types in psoriasis patients

open access: yesChinese Medicine, 2020
Background To analyze the expression of miRNA (microRNA) in peripheral blood mononuclear cells in patients with Psoriasis vulgaris with different TCM syndromes by miRNA chip.
Yue Lu   +11 more
doaj   +1 more source

Multimedia-based Medicinal Plants Sustainability Management System [PDF]

open access: yesIJCSI International Journal of Computer Science Issues, Vol. 8, Issue 5, No 3, September 2011; ISSN (Online): 1694-0814, 2011
Medicinal plants are increasingly recognized worldwide as an alternative source of efficacious and inexpensive medications to synthetic chemo-therapeutic compound. Rapid declining wild stocks of medicinal plants accompanied by adulteration and species substitutions reduce their efficacy, quality and safety.
arxiv  

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