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Otitis media [PDF]

Nature Reviews Disease Primers, 2016
Otitis media (OM) or middle ear inflammation is a spectrum of diseases, including acute otitis media (AOM), otitis media with effusion (OME; 'glue ear') and chronic suppurative otitis media (CSOM). OM is among the most common diseases in young children worldwide.
Schilder, Anne GM, Chonmaitree, Tasnee, Cripps, Allan W, Rosenfeld, Richard M, Casselbrant, Margaretha L, Haggard, Mark P, Venekamp, Roderick P   +6 more
semanticscholar   +9 more sources

Induction of Nitric Oxide and Its Role in Otitis Media [PDF]

Antioxidants
Although many studies have investigated the expression and role of nitric oxide (NO) in various diseases, it remains unclear whether NO has a beneficial or detrimental impact on otitis media. This review examines the literature on the expression and role
Yeon Ju Oh, Jae Min Lee, Joon Hyung Yeo, Sung Soo Kim, Seung Geun Yeo   +4 more
doaj   +2 more sources

The social determinants of otitis media in aboriginal children in Australia: are we addressing the primary causes? A systematic content review

BMC Public Health, 2020
Background Aboriginal and Torres Strait Islander children experience some of the highest rates of otitis media in the world. Key risk factors for otitis media in Aboriginal children in Australia are largely social and environmental factors such as ...
Jack DeLacy, Tinashe Dune, John J. Macdonald   +2 more
doaj   +2 more sources

Understanding the aetiology and resolution of chronic otitis media from animal and human studies

Disease Models & Mechanisms, 2017
Inflammation of the middle ear, known clinically as chronic otitis media, presents in different forms, such as chronic otitis media with effusion (COME; glue ear) and chronic suppurative otitis media (CSOM).
Mahmood F. Bhutta, Ruth B. Thornton, Lea-Ann S. Kirkham, Joseph E. Kerschner, Michael T. Cheeseman   +4 more
doaj   +2 more sources

Tympanostomy Tubes or Medical Management for Recurrent Acute Otitis Media.

New England Journal of Medicine, 2021
BACKGROUND Official recommendations differ regarding tympanostomy-tube placement for children with recurrent acute otitis media. METHODS We randomly assigned children 6 to 35 months of age who had had at least three episodes of acute otitis media ...
A. Hoberman, D. Preciado, J. Paradise, David H. Chi, M. Haralam, S. Block, Diana H. Kearney, S. Bhatnagar, Gysella B Muñiz Pujalt, T. Shope, Judith M. Martin, D. Felten, M. Kurs‐Lasky, Hui Liu, Kristin Yahner, Jong-Hyeon Jeong, N. Cohen, Brian Czervionke, Jennifer P. Nagg, J. Dohar, N. Shaikh   +20 more
semanticscholar   +1 more source

The Impact of the COVID-19 Pandemic on Otitis Media

Viruses, 2022
Otitis media is one of the most common diseases in children, with 80% of children experiencing it by the age of three years. Therefore, the resulting social burden is enormous.
Soo-Young Choi, Dong-Keon Yon, Yong-Sung Choi, Jinseok Lee, Ki-Ho Park, Young-Ju Lee, Sung-Soo Kim, Sang-Hoon Kim, Seung-Geun Yeo   +8 more
doaj   +1 more source

Predominant role of Haemophilus influenzae in the association of conjunctivitis, acute otitis media and acute bacterial paranasal sinusitis in children

Scientific Reports, 2021
Haemophilus influenzae is a predominant pathogen for conjunctivitis, acute otitis media and acute bacterial paranasal sinusitis in children. We undertook this study to investigate the possible association among these diseases.
Ya-Li Hu, P.-I. Lee, P. Hsueh, Chun-Yi Lu, Luan-Yin Chang, Li-Min Huang, Tu-Hsuan Chang, J. Chen   +7 more
semanticscholar   +1 more source

Otitis media in coronavirus disease 2019: a case series

Journal of Laryngology and Otology, 2021
Background Manifestations of the coronavirus disease 2019 in ENT include sore throat, rhinorrhoea, anosmia and dysgeusia. Whether coronavirus disease 2019 causes otitis media is not known.
N. Raad, J. Ghorbani, N. Mikaniki, S. Haseli, M. Karimi-Galougahi   +4 more
semanticscholar   +1 more source

Silencing Nrf2 attenuates chronic suppurative otitis media by inhibiting pro-inflammatory cytokine secretion through up-regulating TLR4

Innate Immunity, 2021
Compromised TLR-mediated chronic inflammation contributes to bacterial infection-caused chronic suppurative otitis media, but the mechanisms are unclear.
Abulajiang Tuoheti, Xingzhi Gu, Xiuqin Cheng, Hua Zhang   +3 more
doaj   +1 more source

Otitis media [PDF]

The Lancet, 2004
Otitis media (OM) continues to be one of the most common childhood infections and is a major cause of morbidity in children. The pathogenesis of OM is multifactorial, involving the adaptive and native immune system, Eustachian-tube dysfunction, viral and bacterial load, and genetic and environmental factors. Initial observation seems to be suitable for
Rovers, M.M., Schilder, A.G.M., Zielhuis, G.A., Rosenfeld, R.M.   +3 more
openaire   +2 more sources