Results 41 to 50 of about 9,048,110 (195)

Otorhinolaryngological Problems in Mucopolysaccharidoses: A Review of Common Symptoms in a Rare Disease

Brain Sciences
Background: The mucopolysaccharidoses (MPSs) are very rare lysosomal diseases. MPSs belong to inherited diseases; however, newborns are usually asymptomatic. A deficiency of one of the enzymes, which is responsible for glycosaminoglycan (GAG) catabolism, results in the accumulation of this material. GAGs lead to progressive damage to tissues. More than
Anna Waśniewska, Renata Pepaś, Oskar Rosiak, Wiesław Konopka   +3 more
openalex   +4 more sources

Fallopian canal arachnoid cyst with acute facial nerve paralysis in children: a report of two cases and literature review

Frontiers in Neurology, 2023
IntroductionSymptoms induced by arachnoid cysts in the fallopian canal are uncommon, and facial nerve paralysis without cerebrospinal fluid otorrhea is comparatively rarer.MethodsHerein, we present two cases of arachnoid cysts in the fallopian canal with
Jianbin Sun, Jianbin Sun, Jianbin Sun, Weiju Han, Weiju Han, Weiju Han   +5 more
doaj   +1 more source

Analysis of GJB2 (Connexin 26) Mutation in Patients with Congenital Non-Syndromic Sensorineural Hearing Loss

Turkish Archives of Otorhinolaryngology, 2014
Objective:This study was performed to investigate the GJB2 (connexin 26) gene mutations that are the most frequent cause of sensorineural deafness in patients with congenital non-syndromic sensorineural hearing loss in our region.Methods:Sixty patients ...
Emin Kaskalan, Ebru Etem Önalan, İrfan Kaygusuz, Turgut Karlıdağ, Erol Keleş, Abdulvahap Akyiğit, Şinasi Yalçın   +6 more
doaj   +1 more source

Computed Tomography-Based Radiomics Model to Predict Central Cervical Lymph Node Metastases in Papillary Thyroid Carcinoma: A Multicenter Study

Frontiers in Endocrinology, 2021
ObjectivesThis study aimed to develop a computed tomography (CT)-based radiomics model to predict central lymph node metastases (CLNM) preoperatively in patients with papillary thyroid carcinoma (PTC).MethodsIn this retrospective study, 678 patients with
Jingjing Li, Jingjing Li, Xinxin Wu, Ning Mao, Ning Mao, Ning Mao, Guibin Zheng, Haicheng Zhang, Yakui Mou, Yakui Mou, Chuanliang Jia, Chuanliang Jia, Chuanliang Jia, Jia Mi, Xicheng Song, Xicheng Song, Xicheng Song   +16 more
doaj   +1 more source

Identification and verification of eight cancer-associated fibroblasts related genes as a prognostic signature for head and neck squamous cell carcinoma

Heliyon, 2023
Cancer-associated fibroblasts (CAFs) can exert their immunosuppressive effects by secreting various effectors that are involved in the regulation of tumor-infiltrating immune cells as well as other immune components in the tumor immune microenvironment ...
Lei Dong, Qi Sun, Fei Song, Xiaoyu Song, Congxian Lu, Yumei Li, Xicheng Song   +6 more
doaj  

Development of a physiological model of human middle ear epithelium

Laryngoscope Investigative Otolaryngology, 2021
Introduction Otitis media is an umbrella term for middle ear inflammation; ranging from acute infection to chronic mucosal disease. It is a leading cause of antimicrobial therapy prescriptions and surgery in children.
Michael William Mather, Bernard Verdon, Rachel Anne Botting, Justin Engelbert, Livia Delpiano, Xin Xu, Catherine Hatton, Tracey Davey, Steven Lisgo, Philip Yates, Nicholas Dawe, Colin D. Bingle, Muzlifah Haniffa, Jason Powell, Chris Ward   +14 more
doaj   +1 more source

SUMOylation is a Translatable Target in Hypoxic MNPs Regulating Retinal Vasculopathy

Advanced Science, EarlyView.
During ischemic retinopathy/retinal vasculopathy, UBC9‐mediated SUMOylation in retinal macrophages enhances their pro‐angiogenic capacity via hypoxia‐induced SUMOylation of FUS at K327/K502. This modification suppresses FUS binding to the Vegfa mRNA 3’UTR, stabilizing transcripts and facilitating VEGFA production. Targeting UBC9 inhibition can serve as
Zheng Zhong, Guangyu Liang, Huimin Yu, Jiaqi Li, Ruohong Wang, Xiaohong Ma, Ziqing Zhou, Yin Zhao, Fei Sun, Xufang Sun   +9 more
wiley   +1 more source

Subcutaneous emphysema with pneumomediastinum after elective tonsillectomy - Case study

Otolaryngology Case Reports, 2021
Tonsillectomy is a common operation in otorhinolaryngology with subcutaneous emphysema with pneumomediastinum being an uncommon, nevertheless, potentially life-threatening complication.
Dimitrios Paouris, Samuel Kunzo, Irina Šebová   +2 more
doaj  

Investigating the mechanisms of capsicum in age‐related hearing loss: Based on network pharmacology

Eye &ENT Research, EarlyView.
Abstract Background To explore the material basis and action mechanism of the chemical component gene of pepper on presbycusis, and to provide a reference for the traditional Chinese medicine treatment of age‐related hearing loss (ARHL). Methods The chemical composition and action targets of traditional Chinese medicine flavor of pepper were searched ...
Yan Wang, Xiaoyu Song, Fengxin Yang, Huhuifen He, Kun Zhao, Jingjing Qiu, Limei Cui, Qiang Zhang, Limei Liu, Yan Sun   +9 more
wiley   +1 more source

Effect of Olfactory Training in COVID‐19 Related Olfactory Dysfunction—A Placebo‐Controlled Trial

The Laryngoscope, EarlyView.
This randomized placebo‐controlled trial evaluates the effectiveness of olfactory training in patients with post‐COVID‐19 olfactory dysfunction. The results showed no significant improvement in olfactory function after 12 weeks of training. The presence of parosmia was associated with reduced effectiveness of the olfactory training.
Ditte Gertz Mogensen, Kasper Aanaes, Ida Brandt Andersen, Mary Jarden, Vibeke Backer   +4 more
wiley   +1 more source