Results 181 to 190 of about 8,213 (210)

[Monitoring hearing during ototoxic cisplatin therapy].

Padiatrie und Grenzgebiete, 1990
In the 1983-1988 period, the audition of 17 children was studied prior to and during antineoplastic chemotherapy with cumulative total cisplatin doses from 270 to 1530 mg/m2. The hearing tests were conducted by means of an objective method which doses not depend on patients' cooperation: the recording of fast auditory evoked potentials.
J, Kluba, U, Kluba, H, von Specht, U, Mittler   +3 more
openaire   +1 more source

Audiologic Monitoring of Ototoxicity

2014
Ototoxicity can be defined as the capacity of a drug or chemical to cause damage to the inner ear structure and\or function. This phenomenon may involve the cochlea, vestibule or both. The symptoms of ototoxicity include hearing loss, tinnitus, and vertigo. Today, the number of audiologic tests for monitoring ototoxicity has increased.
TAŞ, Abdullah, YAĞIZ, Recep
openaire   +1 more source

[Monitoring drug ototoxicity with distortion products].

Acta otorrinolaringologica espanola, 2000
Distortion products are currently considered an objective method for rapidly evaluating the functional status of the cochlea, which is interesting for the monitoring of drug ototoxicity. We studied 40 ears from patients who had received an ototoxic drug, tobramycin.
M, Orts Alborch, A, Morant Ventura, J, García Callejo, F, Ferrer Baixauli, M P, Martínez Beneito, J, Marco Algarra   +5 more
openaire   +1 more source

High-Frequency Audiometric Monitoring Strategies for Early Detection of Ototoxicity

Ear and Hearing, 1994
Therapeutic drugs such as the aminoglycoside antibiotics (AMG) and the chemotherapy agent cisplatin (CDDP) are known to cause irreversible hearing loss, typically affecting highest frequency hearing first with progression of loss to the lower frequency regions.
Fausti, Stephen A., Larson, Vernon D., Noffsinger, Douglas, Wilson, Richard H., Phillips, David S., Fowler, Cynthia G.   +5 more
openaire   +3 more sources

Otoacoustic emissions — an approach for monitoring aminoglycoside induced ototoxicity in children

International Journal of Pediatric Otorhinolaryngology, 1999
The early detection of hearing impairment caused by ototoxic drugs, such as aminoglycosides, has been the aim of research world-wide. Histopathological studies have shown that the outer hair cells are the most susceptible cochlear components to injury from ototoxic drugs like aminoglycosides.
P, Stavroulaki, N, Apostolopoulos, D, Dinopoulou, I, Vossinakis, M, Tsakanikos, D, Douniadakis   +5 more
openaire   +2 more sources

Otoacoustic emissions analysers for monitoring aminoglycosides ototoxicity.

Romanian journal of internal medicine = Revue roumaine de medecine interne, 2010
Aminoglycosides (AG) are widely prescribed despite their notorious toxicity. These antibiotics cause irreversible hearing loss, starting with high frequencies and progressing toward conversational frequencies (0.5-2 kHz), by destroying the acoustic hair cells in the inner ear.
Ruxandra Moroti, Constantinescu, Mădălina, Georgescu, A, Pascu, Adriana, Hristea, Victoria, Aramă, C, Băicuş, Ruxandra Oana, Călin, Eugenia, Kovacs   +7 more
openaire   +1 more source

Gentamicin-induced ototoxicity in a carefully monitored renal-failure patient

American Journal of Health-System Pharmacy, 1981
A case of gentamicin-induced ototoxicity, documented by electronystagmography and audiometry, in a patient with chronic renal failure is presented. A 39-year-old white man was hospitalized for a renal transplant procedure. Multiple postoperative complications included infection, and the transplanted kidney was rejected eventually.
openaire   +2 more sources

G93 Aminoglycoside use and ototoxicity monitoring in UK CF units

Archives of Disease in Childhood, 2014
Background Cystic fibrosis (CF) patients are at high risk of aminoglycoside ototoxicity, causing hearing loss, tinnitus or balance problems which can have significant social and psychological implications. The incidence of aminoglycoside cochlear ototoxicity in CF patients is unclear but incidences up to 21% in children have been quoted.
M. Kikic, G. Al-Malky
openaire   +1 more source

Trends in ototoxicity monitoring among cisplatin-treated patients with cancer

Journal of Cancer Survivorship
This study aims to characterize patterns in ototoxicity monitoring and identify potential barriers to audiologic follow-up.We performed a single-institution retrospective cohort study on adult (≥ 18 years old) cancer patients treated with cisplatin from January 2014 to September 2021.
David S, Lee, Emma Y, Travis, Susan K, Wong, Marie-Ange, Munyemana, Lauren, Mueller, Cathryn Collopy, Rowling, Jason T, Rich, Patrik, Pipkorn, Sidharth V, Puram, Ryan S, Jackson, Douglas R, Adkins, Peter, Oppelt, Wade L, Thorstad, Cameron C, Wick, Jose P, Zevallos, Kate, McClannahan, Angela L, Mazul   +16 more
openaire   +2 more sources

Bedside High Frequency Monitoring for Ototoxicity

Otolaryngology–Head and Neck Surgery, 1997
B SINKS, J GOEBEL
openaire   +1 more source