Results 11 to 20 of about 113,556 (283)

Adeno‐associated virus serotype 2 capsid variants for improved liver‐directed gene therapy

Hepatology, EarlyView., 2022
Abstract Background and Aims Current liver‐directed gene therapies look for adeno‐associated virus (AAV) vectors with improved efficacy. With this background, capsid engineering is explored. Whereas shuffled capsid library screenings have resulted in potent liver targeting variants with one first vector in human clinical trials, modifying natural ...
Nadja Meumann, Marti Cabanes‐Creus, Moritz Ertelt, Renina Gale Navarro, Julie Lucifora, Qinggong Yuan, Karin Nien‐Huber, Ahmed Abdelrahman, Xuan‐Khang Vu, Liang Zhang, Ann‐Christin Franke, Christian Schmithals, Albrecht Piiper, Annabelle Vogt, Maria Gonzalez‐Carmona, Jochen T. Frueh, Evelyn Ullrich, Philip Meuleman, Steven R. Talbot, Margarete Odenthal, Michael Ott, Erhard Seifried, Clara T. Schoeder, Joachim Schwäble, Leszek Lisowski, Hildegard Büning   +25 more
wiley   +1 more source

Bioresource collection of blood components from pregnant women to identify fetal genetic features, as well as to search for genetic markers of gestational complications

Кардиоваскулярная терапия и профилактика, 2023
Aim. To create collection of plasma and leukocyte blood samples from pregnant women to improve methods of non-invasive prenatal testing, as well as to search for deoxyribonucleic acid markers and study the molecular mechanisms of gestational ...
E. S. Vashukova, O. A. Tarasenko, O. E. Talantova, P. Yu. Kozyulina, A. V. Morshneva, А. R. Maltseva, O. V. Pachulia, O. N. Bespalova, I. Yu. Kogan, A. S. Glotov   +9 more
doaj   +1 more source

Una mirada epistemológica sobre el costo de los nuevos bienes de capital

Contabilidad y Auditoría, 2021
El mundo se encuentra ante una nueva etapa de la economía sustentada en grandes infraestructuras globales. Esta infraestructura está compuesta por bienes de capital con componentes virtuales y físicos que deben poder ser entendidos desde el marco ...
Juan Francisco Rodríguez Brites
doaj  

Endometriosis-associated pain and new therapeutic options: A review [PDF]

Гинекология, 2023
Pelvic pain is one of the most common and significant clinical symptoms of endometriosis. The complex pathogenesis and paradoxical nature of endometriosis-associated pain, its chronicity and centralization, a marked decrease in the quality of life of ...
Maria I. Yarmolinskaya, Alexandra K. Beganova, Anastasia S. Revenko   +2 more
doaj   +1 more source

Inventory and quality control of biosample collection from pregnant women at different gestational ages to search for early biomarkers of pregnancy complications

Кардиоваскулярная терапия и профилактика, 2023
Aim. To conduct an inventory and quality control of biosample collection from pregnant women at different gestational ages to search for early biomarkers of pregnancy complications.Material and methods.
A. R. Maltseva, R. A. Illarionov, E. S. Vashukova, O. V. Pachulia, T. B. Postnikova, M. E. Velizhanina, A. A. Rubel, Yu. A. Nasykhova, O. N. Bespalova, A. S. Glotov   +9 more
doaj   +1 more source

The role of survivin in the pathogenesis of genital endometriosis, current application possibilities (literature review) [PDF]

Гинекология, 2020
In the structure of gynecological diseases, genital endometriosis takes the third place, and its frequency tends to increase. Endometriosis occurs in 510% of women of reproductive age, in 3550% of patients with infertility and in 7080% of women with ...
Elena V. Misharina, Maria I. Yarmolinskaya, Tatiana E. Ivashchenko, Nelly Y. Andreyeva   +3 more
doaj   +1 more source

Transverse abdominis plane block as a method of anesthesia after caesarean section

Вестник анестезиологии и реаниматологии, 2023
Although we have various methods of analgesia, the prevalence of severe pain after caesarean section remains high. Therefore, it is necessary to look for new reliable technologies for optimal postoperative anesthesia.The objective was to compare the ...
O. V. Riazanova, V. I. Shadenkov, R. V. Kapustin, I. Yu. Kogan   +3 more
doaj   +1 more source

Microvesicles produced by natural killer cells of the NK-92 cell line affect the phenotype and functions of endothelial cells of the EA.Hy926 cell line

Медицинская иммунология, 2020
Microvesicles (MVs) are small (100-1000 nm) subcellular structures produced by both motionless and activated cells that can transfer molecules to target cells, and regulate physiological and pathological processes.
K. L. Markova, V. A. Mikhailova, A. V. Korenevsky, Yu. P. Milyutina, V. V. Rodygina, E. P. Aleksandrova, A. S. Markov, O. A. Balabas, S. A. Selkov, D. I. Sokolov   +9 more
doaj   +1 more source

Quality management of biosampling and data collection from women at different stages of pregnancy for the search for early biomarkers of preterm birth: predicting errors and risk management

Кардиоваскулярная терапия и профилактика, 2022
The main condition for ensuring effective sampling for creating a bioresource collection is quality management, which implies careful planning and predicting errors at all stages.
O. V. Pachulia, R. A. Illarionov, E. S. Vashukova, N. A. Yurkina, M. G. Butenko, T. B. Postnikova, O. N. Bespalova, A. S. Glotov   +7 more
doaj   +1 more source

Over-the-top (OTT) entertainment viewership addiction among the undergraduates of a medical college in Bhubaneswar, Odisha

Journal of Family Medicine and Primary Care
Background: There has been a sudden surge in the popularity of OTT (Over-the-top) viewership during the recent pandemic mostly among youngsters. This has also influenced their physical, mental, and social health. Objectives: To find the prevalence of OTT
Snigdha Singh, Ipsita Debata, Anugya A. Behera, Prem S. Panda, Aurobindo Samantaray, Basanta K. Behera   +5 more
doaj   +1 more source