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Relationship between ouabain and asthenozoospermia
Journal of Huazhong University of Science and Technology [Medical Sciences], 2014A growing number of researches have shown that ouabain can regulate mammalian sperm function and male reproduction by modulating the sperm motility, capacitation and acrosome reaction in vitro. This study further examined the relationship between ouabain and asthenozoospermia.
Ting Xue+4 more
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Erythrocyte Ouabain Binding in Dementia
Gerontology, 1983Age-matched patients attending a geriatric psychiatry day hospital, one group with Alzheimer's dementia and another with functional illness, were studied and compared with similar inpatient groups. Erythrocyte ouabain binding was assayed and Clifton ratings completed.
Anne M. McHarg+2 more
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Ouabain Antagonists as Antihypertensive Agents
Current Pharmaceutical Design, 2005The evidence that high levels of endogenous ouabain (EO), a closely related isomer of ouabain, are implicated in human hypertension and cardiac hypertrophy and failure stimulated the pharmacological research for developing novel anti-hypertensive agents active as ouabain antagonists.
P. Barassi+7 more
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Modulation of the Immune System by Ouabain
Annals of the New York Academy of Sciences, 2009Ouabain, a known inhibitor of the Na,K‐ATPase, has been shown to regulate a number of lymphocyte functions in vitro and in vivo. Lymphocyte proliferation, apoptosis, cytokine production, and monocyte function are all affected by ouabain. The ouabain‐binding site occurs at the α subunit of the enzyme. The α subunit plays a critical role in the transport
Ottilia R. Affonso-Mitidieri+5 more
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Ouabain Hypoglycemia: Insulin Mediation
Science, 1968The fall in blood sugar occurring during infusion of ouabain (1 microgram per kilogram per minute for a 60-minute period) in dogs is accompanied by an increased uptake of glucose and potassium by the liver. Concurrently, plasma insulin in the portal blood increases significantly.
L. Triner+2 more
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Ouabain on the hypothermic dog heart
American Heart Journal, 1958Abstract The effect of digitalization with ouabain on the susceptibility of the hypothermic heart to ventricular fibrillation (VF) was tested in dogs. Spontaneous VF did not occur with greater frequency in digitalized animals than in controls. Similarly, ouabain did not alter significantly the incidence of VF during experimental ventriculotomy under ...
J. Torres, E.T. Angelakos, R. Driscoll
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Apical ouabain-sensitive and ouabain-insensitive ATPases in rat colonic epithelium
Acta Histochemica, 2002Active resorption of potassium ions in the colon is mediated by ouabain-sensitive and ouabain-insensitive H,K-ATPases localized in the apical membrane of colonic enterocytes (colonocytes). The present study was performed to investigate distribution patterns of apical ATPases using catalytic histochemistry and immunohistochemistry.
Radomíra Vagnerová+3 more
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FISH OSMOREGULATE WITH OUABAIN
Journal of Experimental Biology, 2005![Figure][1] OSMOREGULATION Ouabain, a potent inhibitor of the enzyme Na+/K+-ATPase, is known to be a steroid hormone in mammals that is involved in blood pressure and volume regulation.
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Microinjection of ouabain into crab single muscle fibers and the mechanism of ouabain potentiation
Canadian Journal of Physiology and Pharmacology, 1980In order to clarify the mechanism of the potentiating effect of ouabain on contraction, a study was made of the effect of microinjection of 1.5 μL of ouabain on contractile responses and 22Na efflux, using single muscle fibers of crab (i–iii), and the results obtained were compared with observations (iv) on frog hearts.
Fujino S, Fujino M
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Epileptogenic foci induced with ouabain
Electroencephalography and Clinical Neurophysiology, 1970Abstract In an attempt to produce a model of focal cortical epilepsy, ouabain, an inhibitor of the membrane sodium pump, was applied to the surface of rat cortex. Fifteen of a series of twenty-two animals manifested prominent focal epileptiform discharges in the EEG at some time within the first 24 h, and six rats had observable focal seizures.
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