Results 121 to 130 of about 546,177 (228)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Nursing care management or nursing case management? A scoping review to identify models, roles, and advantages. [PDF]

Nurs Manage
Martella P, Rossi N, Schiavoni E, Napolitano D.   +3 more
europepmc   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

AI-assisted thematic synthesis of existing neurological core outcome sets: A descriptive reference framework (COS-Neuro). [PDF]

PLoS One
Tiong SP, Yang X, Touzet AY, Millward CP, Zipser CM, Tetreault L, Gharooni A, Davies BM.   +7 more
europepmc   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

The development of a multi-level intervention to improve data quality of the national quality indicators in Swiss long-term care facilities using an Intervention Mapping approach. [PDF]

Front Health Serv
Osińska M, Braun D, Baumann S, Benkert B, Curreri N, Huang J, Simon M, Van Grootven B, Zúñiga F.   +8 more
europepmc   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

HOME, the heart of healing: advancing patient safety beyond the hospital. [PDF]

BMJ Open Qual
Al Harbi S, Obaidallah N, Aljuaid E, Diamat K, Selvaraj S, Tolentin H, Alzobidi F, Alshowaier N, Alharthi N, Baldovino FL, Raviz KB.   +10 more
europepmc   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Physicians shortage in primary care: a protocol for updating a systematic review of recruitment and retention strategies. [PDF]

F1000Res
Contu F, Cossu G, Bitti B, Primavera D, Verma P, Forte V, Ford J, Carta MG.   +7 more
europepmc   +1 more source