Results 131 to 140 of about 448,885 (232)

Quality indicators for opioid stewardship interventions in hospital inpatient and emergency departments: a systematic review. [PDF]

Pain Rep
Dutkiewicz C, Jauregui K, Liu S, Dabliz R, Patanwala AE, Penm J.   +5 more
europepmc   +1 more source

FEM1B enhances TRAIL‐induced apoptosis in T lymphocytes and monocytes

FEBS Open Bio, EarlyView.
FEM1B facilitates TRAIL‐induced apoptosis through distinct mechanisms in T lymphocytes and monocytes. In T lymphocytes, FEM1B engages with TRAF2, leading to a reduction in TRAF2 expression, which subsequently lessens TRAF2's inhibitory influence on caspase‐8.
Chenbo Yang, Wenhui Yu, Cui Dang, Jingjing Zhang, Jiahan Lu, Jing Xue   +5 more
wiley   +1 more source

Acceptability, fidelity and implementation of systematic integrated pain management in oncology outpatient services: a process evaluation protocol for a multicentre clustered randomised pilot trial. [PDF]

BMJ Open
Robinson OC, Day F, Boland EG, Collinson M, Fallon M, Farrin A, Flemming K, Girvan S, Hartup S, Meads D, Hurlow A, Mayland C, O'Dwyer J, Pini S, Swinson D, Richards SH, Mulvey MR.   +16 more
europepmc   +1 more source

Earthing effects on mitochondrial function: ATP production and ROS generation

FEBS Open Bio, EarlyView.
In contrast to sham and naive controls, grounded mitochondria not only exhibit significantly enhanced energy production but also demonstrate a remarkable reduction in membrane potential and oxidative stress. This suggests a profound improvement in mitochondrial health, presenting a promising avenue for therapeutic interventions.
Cecilia Giulivi, Richard Kotz
wiley   +1 more source

Effectiveness of adapted self-help plus (SH+) to reduce psychological distress among university students in Indonesia (APRESIASI): protocol of a randomized controlled trial. [PDF]

BMC Psychol
Andriani D, Purba FD, Witteveen AB, Zakiyah N, Sijbrandij M.   +4 more
europepmc   +1 more source

Biophysical characterization and ion transport with cell‐based and proteoliposome reconstitution assays of invertebrate K+‐Cl− cotransporters

FEBS Open Bio, EarlyView.
The K+‐Cl− cotransporters (KCCs) facilitate the symport of ions across the plasma membrane. They participate in physiological processes including neuronal regulation. Here, we characterized KCCs from Drosophila and Hydra vulgaris. Comparative analyses of transporters provide insights into the mechanism of KCC ion transport, regulation, and evolution ...
Satoshi Fudo, Marina Verkhovskaya, Coralie Di Scala, Claudio Rivera, Tommi Kajander   +4 more
wiley   +1 more source

Steps for Planning Health Program Evaluations: From Program Logic to Data Collection and Reporting Plans. [PDF]

Aust J Rural Health
Thomas M, Summers J, Honeywood S, Fitzgerald A, Ambler D, Falciani K, Cook A, Smith K, Bright D, Lindsay M, Sanford C.   +10 more
europepmc   +1 more source

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

FEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

Developing a Framework for Online Review-Based Health Care Service Quality Assessment: Text-Mining Study.

J Med Internet Res
Zhang X, Sun J, Li X, Liu Y, Li C.
europepmc   +1 more source

A study protocol for a randomized controlled feasibility trial of behavioural therapy for interepisode bipolar symptoms (STABILISE). [PDF]

Pilot Feasibility Stud
Wright K, Warren F, Bucci S, Dunn BD, Jones S, O'Mahen H, Taylor RS, Medina-Lara A.   +7 more
europepmc   +1 more source