Results 181 to 190 of about 14,326,866 (362)

Is less more? A preliminary investigation of the number of response categories in self-reported pain

open access: yesPatient Related Outcome Measures, 2010
Karon F Cook1, David Cella2, Erin L Boespflug1, Dagmar Amtmann11Department of Rehabilitation Medicine, University of Washington, Seattle, WA; 2Department of Medical Social Sciences, Northwestern University, Feinberg School of Medicine, Chicago, IL ...
Karon F Cook   +3 more
doaj  

US Hospitals Strive for Quality: A Comparative Study of the Relationship between Hospital Process and Outcome Measures

open access: yes, 2010
[[abstract]]Background As a result of the growing concerns related to quality of care in Unites States Hospitals, the centers for Medicare and Medicaid Services began measuring hospital performance and reporting this performance on their Hospital Compare
Anita Lilian Khodra
core  

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Gout disease-specific quality of life and the association with gout characteristics

open access: yesPatient Related Outcome Measures, 2010
Jan D Hirsch1,4, Robert Terkeltaub4, Dinesh Khanna5, Jasvinder Singh6, Andrew Sarkin2, Micki Shieh2, Arthur Kavanaugh3, Susan J Lee3,41Skaggs School of Pharmacy and Pharmaceutical Sciences, 2Health Services Research, 3Center for Innovative&nbsp ...
Jan D Hirsch   +3 more
doaj  

The Development and Clinical Testing of a Movement Quality Outcome Measure for Patients with Neurological Conditions: The Leeds Movement Performance Index

open access: yes
Background In modern neurological physiotherapy practice, a patient’s neuroplasticity is harnessed, teaching them to develop motor control at ‘impairment’ level.
Ross, Denise Helen
core  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Evaluation of the Content Validity of the COVID-19 Symptoms Daily Diary

open access: yesPatient Related Outcome Measures
Jennifer Dine,1 Yanfen Guan,2 Mirline Milien,1 Claire Ervin,1 Dana D Byrne,2 Michelle L Brown,2 Carisa De Anda,2 Josephine M Norquist2 1RTI Health Solutions, Research Triangle Park, Durham, NC, USA; 2Merck & Co., Inc., Rahway, NJ, USACorrespondence ...
Dine J   +7 more
doaj  

Risk factors for poor health-related quality of life in cancer survivors with multiple chronic conditions: exploring the role of treatment burden as a mediator

open access: yesPatient Related Outcome Measures, 2019
David T Eton,1,2 Roger T Anderson,3 Wendy F Cohn,3 Erin M Kennedy,3 Jennifer L St. Sauver,1,2 Bayly J Bucknell,1 Kathryn J Ruddy4 1Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA; 2Robert D. and Patricia E.
Eton DT   +6 more
doaj  

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

open access: yesFEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino   +2 more
wiley   +1 more source

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