Results 201 to 210 of about 1,496,473 (269)

Mapping Person-Centred Care in Wound Management: A Scoping Review of Frameworks, Concepts and Outcome Measures. [PDF]

Int Wound J
Panfil EM, Soldo F, Probst S.
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Perceptual Outcome Measures for Supplementing Transcription Intelligibility in Speakers with Parkinson's Disease and Mild Dysarthria. [PDF]

Folia Phoniatr Logop
Manes JL, Stipancic KL, Westemeyer L, Rohl A, Greenlee JDW, Narayanan N, Uc E, Tjaden K.   +7 more
europepmc   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Erratum to 'Longitudinal evaluation of patient-reported outcome measures and clinician-based scores after reverse shoulder arthroplasty in Asian patients: patient-reported outcome measures may be sufficient beyond 1 year' [JSES International Volume 10 Issue 3 (2026) 101,646]. [PDF]

JSES Int
Hirakawa Y, Manaka T, Nakazawa K, Ito Y, Ogura A, Takahashi Y, Hasegawa Y, Igawa A, Terai H.   +8 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Barriers and facilitators for implementing patient-reported outcome measures in oncology practices: an umbrella review. [PDF]

Qual Life Res
Rammant E, Ramsey I, M de Ligt K, Mazariego C, Pogoda K, Schmidt H, Beernaert K, Lidington E, Javan RC, Koczwara B, Sztankay M, van de Poll-Franse L, Van Hemelrijck M, EORTC quality of life group.   +13 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Outcomes and outcome measures in studies of pulmonary alveolar proteinosis: a scoping review. [PDF]

Eur Respir Rev
Xiong J, Lei R, Zhang G, Tian X, Gu R, Chen Y, Luo Z.   +6 more
europepmc   +1 more source

Outcome Measures to Assess the Effectiveness of Exercise Interventions on Chemotherapy-Induced Peripheral Neuropathy (CIPN): A Scoping Review. [PDF]

Curr Oncol
Lindstrom TR, Parkinson JF, Courneya KS, McNeely ML.   +3 more
europepmc   +1 more source