Results 21 to 30 of about 10,777,165 (290)

The impact of worker values on client outcomes within a drug treatment service [PDF]

, 2008
Background: Little attention has been paid to understanding the impact of values, attributes and characteristics of drugs workers on therapeutic relationships and treatment outcomes.
Bourne, RHL, Phillips, R
core   +2 more sources

Is the relationship among outcome variables shown in randomized trials? [PDF]

, 2015
BACKGROUND: Randomized controlled trials (RCTs) often have more than one primary outcome and frequently have secondary and harm outcomes. Comparison of outcomes between study arms is the primary focus of RCTs, but there are times when the relation ...
Altman, Douglas, Cooper, Richelle, Lopez-OSullivan, Ana, Schriger, David, Wystrach, Carter   +4 more
core   +1 more source

The effect of delaying initiation with umeclidinium/vilanterol in patients with COPD: an observational administrative claims database analysis using marginal structural models

Multidisciplinary Respiratory Medicine, 2018
Background Chronic obstructive pulmonary disease (COPD) is associated with high clinical and economic burden. Optimal pharmacological therapy for COPD aims to reduce symptoms and the frequency and severity of exacerbations.
Ami R. Buikema, Lee Brekke, Amy Anderson, Eleena Koep, Damon Van Voorhis, Lucie Sharpsten, Beth Hahn, Riju Ray, Richard H. Stanford   +8 more
doaj   +1 more source

Development of a novel patient-reported outcome measure to assess signs and symptoms of COVID-19

Journal of Patient-Reported Outcomes, 2022
Background Given the urgent need for vaccines and treatments for coronavirus disease 2019 (COVID-19), the Symptoms of Infection with Coronavirus-19 (SIC), a comprehensive, patient-reported outcome (PRO) measure of signs and symptoms associated with COVID-
Carla Romano, Sheri Fehnel, Jeffrey Stoddard, Jerald Sadoff, Sandy Lewis, Pauline McNulty, Eric K. H. Chan, Emily Evans, Carol Jamieson, Ashley F. Slagle, Allen Mangel, Kelly McQuarrie   +11 more
doaj   +1 more source

Observational vignette study to examine patient and healthcare provider perceived impact of asthma-related exacerbations in the US

Multidisciplinary Respiratory Medicine, 2019
Background Little is known about how patients and healthcare providers (HCPs) perceive the impact of asthma-related exacerbations. This study examined the impact of asthma-related exacerbations on patients’ lives from these different perspectives ...
Phaedra T. Johnson, Christopher F. Bell, John White, Breanna Essoi, Linda Nelsen, Carlyne M. Averell   +5 more
doaj   +1 more source

Qualitative research to explore the symptoms and impacts experienced by children with ulcerative colitis

Journal of Patient-Reported Outcomes, 2020
Background Ulcerative Colitis (UC) is a chronic gastrointestinal disease that often presents during one’s most productive years and is characterized by colon inflammation.
Jason A. Randall, Aiste Guobyte, Laure Delbecque, Louise Newton, Tara Symonds, Theresa Hunter   +5 more
doaj   +1 more source

Key measurement concepts and appropriate clinical outcome assessments in pediatric achondroplasia clinical trials

Orphanet Journal of Rare Diseases, 2022
Background This study aimed to identify fit-for-purpose clinical outcome assessments (COAs) to evaluate physical function, as well as social and emotional well-being in clinical trials enrolling a pediatric population with achondroplasia.
Natalie V. J. Aldhouse, Helen Kitchen, Chloe Johnson, Chris Marshall, Hannah Pegram, Sheryl Pease, Sam Collins, Christine L. Baker, Katherine Beaverson, Chandler Crews, Jill Massey, Kathleen W. Wyrwich   +11 more
doaj   +1 more source

Outcomes and outcome measures

Haemophilia
AbstractIntroductionAdvances in haemophilia treatment have resulted in a near‐normal life expectancy, lower burden of bleeding and treatment, and improved quality of life in high‐income countries. Bleeding rate is approaching zero and novel parameters should be evaluated to assess the efficacy of treatment not only from the clinical point of view by ...
Giancarlo Castaman, Victor Jimenez‐Yuste, Samanta Gouw, Roseline D'Oiron   +3 more
openaire   +2 more sources

A systematic review of goal attainment scaling implementation practices by caregivers in randomized controlled trials

Journal of Patient-Reported Outcomes
Background Goal attainment scaling (GAS), an established individualized, patient-centred outcome measure, is used to capture the patient’s voice. Although first introduced ~60 years ago, there are few published guidelines for implementing GAS, and almost
Kulpreet Cheema, Taylor Dunn, Chere Chapman, Kenneth Rockwood, Susan E. Howlett, Gunes Sevinc   +5 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source