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Lipopolysaccharide Export to the Outer Membrane
2011In this chapter we will discuss how lipopolysaccharide (LPS) is transported and assembled from its site of synthesis (the cytoplasm and the inner membrane) to the cell surface. This is a remarkably complex process, as LPS must traverse three different cellular compartments to reach its final destination.
P. Sperandeo, G. Deho', A. Polissi
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Methanotroph Outer Membrane Preparation
2011All presently known methanotrophs are gram-negative bacteria suggesting that they are surrounded by a two-layered membrane: an inner or cytoplasmic membrane and an outer membrane. In the methanotroph Methylococcus capsulatus (Bath), separation of the two membranes has allowed studies on protein and lipid composition of the outer membrane.
Odd A, Karlsen +3 more
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Getting Into and Through the Outer Membrane
Science, 2007The structures of two related bacterial membrane proteins help to understand protein transport processes in the outer membranes of bacteria, mitochondria, and chloroplasts.
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Biogenesis of Outer Membrane Proteins
2003The cell envelope of Gram-negative bacteria consists of two membranes, the inner membrane, which is a phospholipid bilayer, and the outer membrane, which is an asymmetrical bilayer with phospholipids and lipopolysaccharides (LPS) in the inner and outer monolayers, respectively. The membranes are separated by the peptidoglycan-containing periplasm. Both
Tommassen, J.P.M., Voulhoux, J.R.
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Acinetobacter baumannii outer membrane protein a modulates the biogenesis of outer membrane vesicles
The Journal of Microbiology, 2012Acinetobacter baumannii secretes outer membrane vesicles (OMVs) during both in vitro and in vivo growth, but the biogenesis mechanism by which A. baumannii produces OMVs remains undefined. Outer membrane protein A of A. baumannii (AbOmpA) is a major protein in the outer membrane and the C-terminus of AbOmpA interacts with diaminopimelate of ...
Dong Chan, Moon +7 more
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Lipoproteins and Their Trafficking to the Outer Membrane
EcoSal Plus, 2019Lipoproteins are produced by both Gram-positive and Gram-negative bacteria. Once secreted, lipoproteins are quickly acylated, anchoring them into the plasma membrane. Recent work has shown that Gram-positive bacteria are able to generate considerable diversity in the acylation of their lipoproteins, though the mechanisms involved are only ...
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Outer-Membrane Permeability of Bacteria
CRC Critical Reviews in Microbiology, 1986Gram-negative bacteria evolved to survive under the conditions in which a number of hazardous compounds are abundant. The outer membrane which protects the cell interior acts as a barrier against such hazardous agents, yet the cells must incorporate the chemicals that are essential for the cellular activity.
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Assembly of Bacterial Outer Membrane Proteins
2012Various methods that are routinely used to study the subcellular localization of membrane proteins in wild-type Gram-negative bacteria fall short in genetic studies addressing the biogenesis of outer membrane proteins (OMPs). Here, we describe three biochemical methods that can be used in such studies to evaluate the proper assembly of OMPs into the ...
Grijpstra, J. +2 more
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The Outer Membrane of Gram-negative Bacteria and the Cytoplasmic Membrane
2004The major permeability barrier in any membrane is the lipid bilayer structure, and its barrier property is inversely correlated with its fluidity. Bacteria cannot make this membrane much less fluid or it will start to interfere with the normal functions of the membrane proteins, so some bacteria have constructed an additional structure that surrounds ...
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Physical properties of the bacterial outer membrane
Nature Reviews Microbiology, 2021Thomas Šilhavý +2 more
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