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Mycobacterial outer membranes: in search of proteins [PDF]
The cell wall is a major virulence factor of Mycobacterium tuberculosis and contributes to its intrinsic drug resistance. Recently, cryo-electron microscopy showed that mycobacterial cell wall lipids form an unusual outer membrane. Identification of the components of the uptake and secretion machinery across this membrane will be crucial for ...
Niederweis, M. +4 more
openaire +3 more sources
Fractional exponential decay of a membrane protein population due to capture by coated pits [PDF]
We consider the lateral diffusion of receptors, or other membrane proteins, in the outer membranes of certain cells, and their capture by coated pits. It is shown, for the case in which the coated pits are in fixed random positions, that the long-time ...
Opheusden, J.H.J. van, Wiegel, F.W.
core +12 more sources
High yield production process for Shigella outer membrane particles. [PDF]
Gram-negative bacteria naturally shed particles that consist of outer membrane lipids, outer membrane proteins, and soluble periplasmic components. These particles have been proposed for use as vaccines but the yield has been problematic.
Francesco Berlanda Scorza +11 more
doaj +1 more source
Background Integral membrane proteins constitute about 20–30% of all proteins in the fully sequenced genomes. They come in two structural classes, the α-helical and the β-barrel membrane proteins, demonstrating different physicochemical characteristics ...
Hamodrakas Stavros J +3 more
doaj +1 more source
Translocation and insertion of precursor proteins into isolated outer membranes of mitochondria [PDF]
Nuclear-encoded proteins destined for mitochondria must cross the outer or both outer and inner membranes to reach their final sub- mitochondrial locations. While the inner membrane can translocate preproteins by itself, it is not known whether the outer
Lill, Roland +2 more
core +2 more sources
Insights into outer membrane protein crystallization [PDF]
Outer membrane proteins are structurally distinct from those that reside in the inner membrane and play important roles in bacterial pathogenicity and human metabolism. X-ray crystallography studies on >40 different outer membrane proteins have revealed that the transmembrane portion of these proteins can be constructed from either beta-sheets or less ...
Newstead, S +4 more
openaire +3 more sources
Evolutionary pathways of repeat protein topology in bacterial outer membrane proteins
Outer membrane proteins (OMPs) are the proteins in the surface of Gram-negative bacteria. These proteins have diverse functions but a single topology: the β-barrel.
Meghan Whitney Franklin +5 more
doaj +1 more source
Mitochondrial import receptors for precursor proteins [PDF]
The specific targeting of precursor proteins synthesized in the cytosol to various cell organelles is a central aspect of intracellular protein traffic. Several hundred different proteins are imported from the cytosol into the mitochondria.
Attardi +34 more
core +1 more source
Biogenesis of mitochondrial porin [PDF]
We review here the present knowledge about the pathway of import and assembly of porin into mitochondria and compare it to those of other mitochondrial proteins.
A. Grossmann +74 more
core +1 more source
Transport of proteins into mitochondria [PDF]
Translocational intermediates of precursor proteins of ATPase F1β subunit and cytochrome c1 across mitochondrial membranes were analyzed using two different approaches, transport at low temperature and transport after binding of precursor proteins to ...
Neupert, Walter, Schleyer, Manfred
core +1 more source

