Results 121 to 130 of about 84,904 (290)

Isolation and immunogenicity of extracted outer membrane vesicles from Pseudomonas aeruginosa under antibiotics treatment conditions

open access: yesIranian Journal of Microbiology, 2021
Background and Objectives: Different types of antibiotics have been indicated to enhance the secretion of OMVs from Pseudomonas aeruginosa. We aimed to investigate the effect of meropenem and amikacin antibiotics on inducing the secretion of OMVs and ...
Mehdi Hadadi-Fishani   +4 more
doaj  

Engineered Exosomal miR‐146a‐5p Reprograms BMSC Fate and Restores Mitochondrial Homeostasis in Glucocorticoid‐Induced Osteonecrosis of Femoral Head

open access: yesAdvanced Science, EarlyView.
Exosomal miR‐146a‐5p is identified as a pivotal regulator in steroid‐induced osteonecrosis. Its reduction activates NF‐κB signaling, compromises mitophagy, and disrupts mitochondrial bioenergetics, resulting in autophagic disequilibrium. Engineered exosomes delivering miR‐146a‐5p reinstate mitochondrial function, augment oxidative phosphorylation and ...
Zehui Lv   +13 more
wiley   +1 more source

NlpI-mediated modulation of outer membrane vesicle production through peptidoglycan dynamics in Escherichia coli. [PDF]

open access: yes, 2015
Outer membrane vesicles (OMVs) are ubiquitously secreted from the outer membrane (OM) of Gram-negative bacteria. These heterogeneous structures are composed of OM filled with periplasmic content from the site of budding.
Schwechheimer, Carmen   +2 more
core   +1 more source

The Development of the Eye in the Binni Barbus Sharpeyii Gunther

open access: yesIbn Al-Haitham Journal for Pure and Applied Sciences, 2005
The embryonic development of the eye in Barbuc sharpyeii has been investigated. The first sign of the eye development represented by evagination on both sides of the forebrain anlage 1n embryo at (27) hrs. after fertilization.
N.A. Al-Bakri
doaj   +1 more source

A Biomimetic Dual‐Targeting Nano‐APA‐Editor Reprograms the 3'UTR Landscape for Tongue Squamous Cell Carcinoma Therapy

open access: yesAdvanced Science, EarlyView.
This study unveils a pathogenic axis in oral cancer where NUDT21 suppresses a tumor suppressor network, prominently PTEN, via 3'UTR lengthening. To exploit this transcriptomic vulnerability, we developed a biomimetic Nano‐APA‐editor. By delivering CRISPR/Cas9, we reprogrammed the global 3'UTR landscape, restoring multi‐target tumor suppression and ...
Yiran Ao   +5 more
wiley   +1 more source

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

open access: yesHepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario   +12 more
wiley   +1 more source

Analysis of outer membrane vesicle associated proteins isolated from the plant pathogenic bacterium pv. campestris-1 [PDF]

open access: yes, 2011
H an LPS-specific silver stain. The gel displays different bands resembling: (I) mature LPS consisting of the O-antigen, the core region attached to lipid-A; (II) LPS biosynthesis intermediates with incomplete O-antigen; (III) Lipid A attached to the ...
Vishaldeep K Sidhu (86201)   +3 more
core   +1 more source

Bordetella Pertussis And Outer Membrane Vesicles

open access: yes, 2022
Bordetella pertussis is the causative agent of a respiratory infection called pertussis (whooping cough) that can be fatal in newborns and infants. The pathogen produces a variety of antigenic compounds which alone or simultaneously can damage various host cells.
Colak, Cigdem Yilmaz   +1 more
openaire   +1 more source

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

open access: yesAdvanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng   +9 more
wiley   +1 more source

Analysis of outer membrane vesicle associated proteins isolated from the plant pathogenic bacterium pv. campestris-5 [PDF]

open access: yes, 2011
H an LPS-specific silver stain. The gel displays different bands resembling: (I) mature LPS consisting of the O-antigen, the core region attached to lipid-A; (II) LPS biosynthesis intermediates with incomplete O-antigen; (III) Lipid A attached to the ...
Vishaldeep K Sidhu (86201)   +3 more
core   +1 more source

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