Experimental studies using OMV in a new platform of SARS-CoV-2 vaccines
Human Vaccines and Immunotherapeutics, 2021 Although COVID-19 vaccines have recently been approved for emergency use, search for new vaccines are still urgent, since the access of the countries, especially the poorest, to the vaccines, has shown to be slower than the necessary to rapidly control ...
Prudencio Cr +2 more
exaly +2 more sources
Human Vaccines and Immunotherapeutics, 2017 The protein composition of an Outer Membrane Vesicle (OMV) preparation that constitutes the active pharmaceutical ingredient of VA-MENGOC-BC®, an effective vaccine against Neisseria meningitidis serogroups B, and C is presented.
Luis Javier Gonzalez +2 more
exaly +2 more sources
Periplasmic crowding and peptidoglycan hydrolase activity as drivers of outer membrane vesiculation in Acinetobacter baumannii [PDF]
Communications BiologyAcinetobacter baumannii produces outer membrane vesicles (OMVs) to alleviate envelope stress, though the mechanisms remain poorly understood. To induce periplasmic accumulation of misfolded proteins and trigger stress, a degP mutant is exposed to ...
Bitnara Kim +4 more
doaj +2 more sources
OMV Vaccines and the Role of TLR Agonists in Immune Response [PDF]
International Journal of Molecular Sciences, 2020 Outer Membrane Vesicles (OMVs) are bacterial nanoparticles that are spontaneously released during growth both in vitro and in vivo by Gram-negative bacteria. They are spherical, bilayered membrane nanostructures that contain many components found within the external surface of the parent bacterium.
Francesca Micoli +2 more
exaly +3 more sources
Angiopep-2-decorated bacterial outer membrane vesicles penetrate the blood-brain barrier for glioblastoma chemo-immunotherapy [PDF]
Drug DeliveryGlioblastoma (GBM) therapy remains one of the most formidable challenges in oncology because of the blood-brain barrier (BBB), immunosuppressive tumor microenvironment, and drug resistance.
Pir Tariq Shah +11 more
doaj +2 more sources
Impact of meningococcal group B OMV vaccines, beyond their brief
Human Vaccines and Immunotherapeutics, 2018 Meningococcal group B outer membrane vesicle vaccines have been used widely in Cuba, New Zealand, and Brazil. They are immunogenic and initially assessed largely by their ability to induce serum bactericidal activity.
Helen Petousis-Harris
exaly +2 more sources
Outer membrane vesicles hijack TIM-1 for cellular uptake. [PDF]
PLoS PathogensOuter membrane vesicles (OMVs) are nanoscale proteoliposomes shed by Gram-negative bacteria that mediate host-pathogen interactions and hold promise as platforms for vaccines and targeted drug delivery.
Craig R MacNair +7 more
doaj +2 more sources
Does the syn- versus post-rift thickness ratio have an impact on the inversion-related structural style? [PDF]
Solid Earth, 2023 Many extensional basins worldwide are modified by subsequent compressional episodes, which lead to inverted structures. The structures associated with the reactivation of pre-existing faults are critically important in the formation of suitable ...
A. Tamas +7 more
doaj +1 more source
Wettability Changes Due to Nanomaterials and Alkali—A Proposed Formulation for EOR
Nanomaterials, 2021 We investigated the usage of two silica nanomaterials (surface-modified) and alkali in enhanced oil recovery through Amott spontaneous imbibition tests, interfacial tension (IFT) measurements, and phase behavior.
Samhar Saleh +5 more
doaj +1 more source
Sorption of Nanomaterials to Sandstone Rock
Nanomaterials, 2022 We investigated the interaction of silica nanostructured particles and sandstone rock using various experimental approaches, such as fluid compatibility, batch sorption and single-phase core-floods.
Christian Scheurer +4 more
doaj +1 more source