Results 31 to 40 of about 10,092 (247)

LPS Remodeling Triggers Formation of Outer Membrane Vesicles in Salmonella

open access: yesmBio, 2016
Outer membrane vesicles (OMV) are proposed to mediate multiple functions during pathogenesis and symbiosis. However, the mechanisms responsible for OMV formation remain poorly understood.
Wael Elhenawy   +5 more
doaj   +1 more source

Sodium Taurocholate Stimulates Campylobacter jejuni Outer Membrane Vesicle Production via Down-Regulation of the Maintenance of Lipid Asymmetry Pathway

open access: yesFrontiers in Cellular and Infection Microbiology, 2019
Campylobacter jejuni outer membrane vesicles (OMVs) contain numerous virulence-associated proteins including the cytolethal distending toxin and three serine proteases. As C.
Cadi Davies   +9 more
doaj   +1 more source

OMV-delivered CdtV triggers DNA damage signaling and G2 arrest in epithelial and microvascular endothelial cells.

open access: yes, 2017
(A) Activation of DNA damage G2 checkpoint signaling in Caco-2 cells, HBMEC and HRGEC incubated with O157, TA153 (CdtV-positive control), or TA154 (vector control) OMVs for 20 h or left untreated (no OMV) as demonstrated by immunoblotting of cell lysates
Xiaohua He (361530)   +14 more
core   +1 more source

Preferential Packing of Acidic Glycosidases and Proteases into Bacteroides Outer Membrane Vesicles

open access: yesmBio, 2014
Outer membrane vesicles (OMV) are spherical membranous structures released from the outer membrane (OM) of Gram-negative bacteria. OMV have been proposed to play several different roles during both pathogenesis and symbiosis.
Wael Elhenawy   +2 more
doaj   +1 more source

Antitumor effects of Escherichia coli-derived outer membrane vesicles loaded with ferrous sulfide on oral squamous cell carcinoma [PDF]

open access: yesKouqiang yixue
Objective To evaluate the therapeutic efficacy of OMV@FeS against oral squamous cell carcinoma(OSCC). Methods Escherichia coli-derived outer membrane vesicle (OMV) was extracted using ultracentrifugation and co-precipitated with FeS to form OMV@FeS.
LI Ang, GUO Shuqi, MENG Jian, SHAN Xuelong, LIU Zhen, ZHU Shenghui
doaj   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

open access: yesAdvanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li   +7 more
wiley   +1 more source

Reversing Macrophage Immunometabolic Dysfunction in Prolonged Infections Via a Glutaminolysis‐Fueled Restoration‐Based Hierarchically Selective Therapeutic System

open access: yesAdvanced Science, EarlyView.
A hierarchically selective immunotherapeutic nanoplatform, mGls@HEV‐MTP, selectively restores macrophage immunocompetence through GLS1‐mediated restoration of glutaminolysis‐fueled anaplerosis. Concurrently, it renders Staphylococcus aureus (S. aureus) more readily recognizable to the metabolically reprogrammed macrophages, thereby facilitating ...
Weinan Yang   +17 more
wiley   +1 more source

B cell activation by outer membrane vesicles--a novel virulence mechanism.

open access: yesPLoS Pathogens, 2010
Secretion of outer membrane vesicles (OMV) is an intriguing phenomenon of Gram-negative bacteria and has been suggested to play a role as virulence factors.
Maria Laura A Perez Vidakovics   +6 more
doaj   +1 more source

OpcA and PorB are novel bactericidal antigens of the 4CMenB vaccine in mice and humans

open access: yesnpj Vaccines, 2023
The ability of Neisseria meningitidis Outer Membrane Vesicles (OMV) to induce protective responses in humans is well established and mainly attributed to Porin A (PorA). However, the contribution of additional protein antigens to protection remains to be
Viola Viviani   +13 more
doaj   +1 more source

OMV-associated virulence proteins differentially separate from OMVs during intracellular trafficking.

open access: yes, 2017
(A) CLSM of HBMEC exposed to 5791/99 OMVs for 30 min at 4°C (OMV binding; panels 0 min) followed by 15 min to 20 h at 37°C (OMV internalization). The indicated single fluorescence channels are shown in the right panels (enlargements are displayed in S9 ...
Xiaohua He (361530)   +14 more
core   +1 more source

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