Results 51 to 60 of about 10,092 (247)

TLR9 participates in OMV-dependent B cell activation.

open access: yes, 2013
(A) B cell proliferation was measured by means of [methyl-3H]-thymidine incorporation after 96 h. OMV from the MID-expressing M. catarrhalis wild type (OMV) were combined with different additives as indicated in the figure.
Matthias Mörgelin (109607)   +6 more
core   +1 more source

Nanomedicine‐driven innovations in postoperative cancer immunotherapy: Remodeling tumor microenvironment and precision delivery strategies

open access: yesBMEMat, EarlyView.
Nanomedicine‐Driven Strategies for Suppressing Postoperative Tumor Recurrence. This schematic illustrates three pivotal nanomedical strategies that synergistically counteract recurrence by targeting residual disease and the immunosuppressive tumor microenvironment within the surgical cavity.
Lisong Pang   +8 more
wiley   +1 more source

Interaction of PTX3 with OMV.

open access: yes, 2015
Microtiter plates were coated with OMV (1 μg/well) and binding of PTX3 (a, b) or CRP (c) is presented as mean absorbance at 450 nm (A450) ± SD of triplicate wells. For each experimental setting data are from one out of three independent experiments.
Alberto Mantovani (287283)   +14 more
core   +1 more source

From pathogen to “living drug factory” innovative strategies and clinical translation of bacteria as programmable intelligent vectors for cancer therapy

open access: yesBMEMat, EarlyView.
Engineered bacteria serve as smart, living therapeutics that target tumors, deliver drugs, and remodel immunosuppressive microenvironments. This review highlights their potential to potentiate immunotherapy, radiotherapy, and chemotherapy, offering a promising paradigm for precise and synergistic cancer treatment. Abstract The dynamic interplay between
Haonan Shen   +9 more
wiley   +1 more source

OMV cause up-regulation of B cell surface markers.

open access: yes, 2013
OMV induced changes in expression of HLA-DR (A), CD86 (B), CD69 (C) and CD45 (D). Surface expression of B cell activation markers after OMV stimulation was analyzed by flow cytometry.
Matthias Mörgelin (109607)   +6 more
core   +1 more source

Bacterial Outer Membrane Vesicle-Mediated Cytosolic Delivery of Flagellin Triggers Host NLRC4 Canonical Inflammasome Signaling

open access: yesFrontiers in Immunology, 2020
Bacteria-released components can modulate host innate immune response in the absence of direct host cell–bacteria interaction. In particular, bacteria-derived outer membrane vesicles (OMVs) were recently shown to activate host caspase-11-mediated non ...
Jungmin Yang   +6 more
doaj   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

open access: yesBMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim   +9 more
wiley   +1 more source

Protective Passive Immunity in Escherichia coli ETEC-Challenged Neonatal Mice Conferred by Orally Immunized Dams with Nanoparticles Containing Homologous Outer Membrane Vesicles

open access: yesVaccines, 2020
Enterotoxigenic Escherichia coli (ETEC) strains are a major cause of illness and death in mammals, including neonatal, recently weaned pigs and infant human beings.
Jose Matías   +3 more
doaj   +1 more source

Modelos de negocios para OMV en el Ecuador [PDF]

open access: yes, 2013
En el presente trabajo definimos el concepto de un OMV y su situación en el país, se da a conocer el proyecto de ley para este tipo de operador móvil.
Inga, Juan   +5 more
core   +1 more source

Harnessing bacterial extracellular vesicles for bone and cartilage organoids

open access: yesBMEMat, EarlyView.
This review presents bacterial extracellular vesicles (BEVs) as programmable bioactive regulators for bone and cartilage organoids by delivering functional cargos that modulate skeletal remodeling. It highlights key engineering strategies and future directions to advance next‐generation organoid models for bone aging related diseases.
Han Liu   +8 more
wiley   +1 more source

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