Results 141 to 150 of about 91,336 (295)

Inclusion of proteins into isolated mitochondrial outer membrane vesicles [PDF]

, 1994
Lill, Roland, Neupert, Walter, Driessen, Arnold, Celis, Julio E., Mayer, Andreas   +4 more
core   +1 more source

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

Advanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng, Pengfei Yan, Peng Liu, Chang Yan, Mengqi Zhao, Zuyong Wang, Chao Ma, Rongkai Zhang, Xi Cui, Swee Hin Teoh   +9 more
wiley   +1 more source

Parabacteroides distasonis-Derived Outer Membrane Vesicles Enhance Antitumor Immunity Against Colon Tumors by Modulating CXCL10 and CD8+ T Cells

Rongyao Liang,1,* Pei Li,1,2,* Na Yang,1 Xiaoyi Xiao,1 Jing Gong,1 Xingyuan Zhang,1 Yunuan Bai,1 Yanlong Chen,1 Zhiyong Xie,3 Qiongfeng Liao1 1School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong ...
Yang N, Zhang X, Xie Z, Xiao X, Li P, Liao Q, Chen Y, Gong J, Bai Y, Liang R   +9 more
core  

Porin Loss Impacts the Host Inflammatory Response to Outer Membrane Vesicles of Klebsiella pneumoniae

, 2016
Antibiotic-resistant strains of Klebsiella pneumoniae often exhibit porin loss. In this study, we investigated how porin loss impacted the composition of secreted outer membrane vesicles as well as their ability to trigger proinflammatory cytokine ...
Bethaney K. Cahill, Debra N. Brunson, Cahill, Bethaney K., Sarah K. Dilello, Dedra Gutel, Brunson, Debra N., Ellis, Terri N., Turner, Kelli L., Gutel, Dedra, Terri N. Ellis, Dilello, Sarah K., Kelli L. Turner, Sebastián Albertí, Albertí, Sebastián   +13 more
core   +1 more source

Adversarial Erasing Enhanced Multiple Instance Learning (siMILe): Discriminative Identification of Oligomeric Protein Structures in Single Molecule Localization Microscopy

Advanced Intelligent Systems, EarlyView.
Hallgrimson et al. introduce a machine learning algorithm, siMILe, that takes features of single‐molecule localization microscopy localization clusters (e.g., size and sphericity) and finds the clusters that are associated with certain cell conditions (such as differential protein expression or drug treatment).
Christian Hallgrimson, Y. Lydia Li, Claire A. Shou, Ben Cardoen, John Lim, Timothy H. Wong, Ismail M. Khater, Ivan Robert Nabi, Ghassan Hamarneh   +8 more
wiley   +1 more source

Identification and Structural Characterisation of Novel Outer Membrane Proteins in the genus Borrelia

Although considered Gram-negative the outer membrane (OM) of Borrelia is unique, consisting of a variety of glycolipids, a significant number of surface exposed lipoproteins and a smaller number of integral membrane-spanning β-barrels.
Dyer, Adam
core  

Exosome‐mediated gut–brain axis signaling in neurodegenerative diseases: Mechanisms, experimental evidence, and therapeutic perspectives—A narrative review

Animal Models and Experimental Medicine, EarlyView.
The gut–brain axis is a bidirectional communication network between the intestines and brain, mediated by gut microbiota and exosomes, that regulates neuroinflammation, protein aggregation, and neuronal health processes central to neurodegenerative diseases.
Waheeb Sami Aggad, Rakesh Ghosh, Hailah M. Almohaimeed, Zuhair M. Mohammedsaleh, Fayez M. Saleh, Amany I. Almars, S. Renuka Jyothi, Rajashree Panigrahi, Ajoy Kumer, Bikram Dhara   +9 more
wiley   +1 more source

Viral Mimetic Bacterial Outer Membrane Vesicles for Targeting Angiotensin-Converting Enzyme 2

Gna Ahn,1,2,* Hyo-Won Yoon,1,* Ju Hwan Jeong,3,4,* Yang-Hoon Kim,1,* Woo-Ri Shin,1,5,6 Min-Suk Song,3 Ji-Young Ahn1 1Department of Microbiology, Chungbuk National University, Cheongju, Republic of Korea; 2Center for Ecology and ...
Jeong JH, Kim YH, Shin WR, Yoon HW, Ahn G, Song MS, Ahn JY   +6 more
core  

Helicobacter pylori-derived outer membrane vesicles contribute to Alzheimer's disease pathogenesis via C3-C3aR signalling

, 2023
The gut microbiota represents a diverse and dynamic population of microorganisms that can influence the health of the host. Increasing evidence supports the role of the gut microbiota as a key player in the pathogenesis of neurodegenerative diseases ...
Wierda, Keimpe, Vlaeminck, Ine, De Groef, Lies, Vandenbroucke, RoosmarijnCA05WE140019996423678010016057120000-0002-8327-620XF6617AF2-F0ED-11E1-A9DE-61C894A0A6B4, EL Andaloussi, Samir, Van Imschoot, GrietWE14801001278033F589247C-F0ED-11E1-A9DE-61C894A0A6B4, Van Wonterghem, ElienWE148020009075900009-0008-0027-485X30CFFDEE-F0EE-11E1-A9DE-61C894A0A6B4, Xie, Junhua0001803122868020030093599785567010127E451A84-C5CA-11E8-8987-A2685607D3EF, De Witte, ChloëCA20UZGent0000801414978020018957780000-0002-7632-105X10710020-F0EE-11E1-A9DE-61C894A0A6B4, Pauwels, Marie00012047884880200270461991902671077007DB8682-F0EF-11E1-A197-91C894A0A6B4, Cools, LienWE14000221551434802004234589205bd098-6795-11ed-b255-8f622e35c91e, Van Hoecke, LienWE140000903059868020020093501F1D02F4-F0EE-11E1-A9DE-61C894A0A6B4, Haesebrouck, FreddyDI058010005165810000-0002-1709-933XF4151B78-F0ED-11E1-A9DE-61C894A0A6B4   +12 more
core  

Spatial Cell Death and Oxidative Stress Dynamics in Gas Plasma‐Treated Tumor Tissues

Advanced NanoBiomed Research, EarlyView.
Schematic representation of the four experimental models to study tissue penetration and oxidation. Four tissue models were used. Human pancreatic cancer cells were grown on the chorioallantois membrane of chicken embryos and gas plasma‐treated in ovo, murine colorectal tumor tissue was gas plasma‐exposed ex vivo, murine squamous cell carcinoma cells ...
Anke Schmidt, Shahrzad Rokhsary, Linus Hübner, Lea Miebach, Sander Bekeschus   +4 more
wiley   +1 more source