Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
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Altered microbial cargo in fecal microbiome-derived outer membrane vesicles as novel biomarkers for vascular dementia. [PDF]
Li X +8 more
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Membranous dysmenorrhea and decidual casts: A scoping review
Abstract Background Membranous dysmenorrhea, characterized by the expulsion of intact endometrial tissue rather than gradual dissolution during menstruation, occasionally presents as a decidual cast—a complete triangular mold of the uterine cavity. This poorly understood condition is likely underdiagnosed.
Lovisa Brehmer, Hedvig Engberg
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Characterization of <i>Helicobacter pylori</i> Outer Membrane Vesicles over time, in biofilm and planktonic phenotypes. [PDF]
Puca V +8 more
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Engineering Bacteria for Medicine: Delivery, Diagnosis, and Therapy
ABSTRACT With rapid advances in synthetic biology and genetic engineering, genetically engineered bacteria (GEB) have emerged as a promising platform for biological therapy, addressing key limitations of conventional drug delivery systems and demonstrating significant clinical potential.
Shiyu Xia +11 more
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Frontiers in bacterial outer membrane vesicles: From basic characteristics to cancer therapy. [PDF]
Ma S +6 more
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Microbiome—pancreatic cancer crosstalk: From tumor biology to therapeutic intervention
The intratumoral microbiome acts as a critical regulator in pancreatic cancer progression and therapeutic resistance. This comprehensive review delineates the origins of pancreatic microbes, elucidates their multifaceted mechanisms in driving immune suppression, metabolic reprogramming, and stromal desmoplasia, and highlights the clinical potential of ...
Yuqin Xie +12 more
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Escherichia coli Nissle 1917 alleviates Alzheimer's disease in mice through OmpA-containing outer membrane vesicles. [PDF]
Xie J +13 more
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From ecological principles to precision engineering of plant microbiomes for sustainable agriculture. The plant holobiont integrates diverse microbial niches (including rhizosphere, endosphere, phyllosphere, seed, and aerial‐root mucilagesphere), host genetics (namely M genes), and host metabolites. Furthermore, molecular dialogues, including rhizobial
Mi Wei +26 more
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<i>Vibrio vulnificus</i> outer membrane vesicles induce mitochondrial dysfunction in macrophages via the TNF signaling pathway. [PDF]
Li J +6 more
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