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Purification of Borrelia burgdorferi Outer Membrane Vesicles
Bacterial outer membrane vesicles (OMVs) are spherical membrane constructs shed by gram-negative bacteria. OMVs produced by the Lyme disease pathogen Borrelia burgdorferi have been identified to contain such virulence factors as OspA, OspB, OspC, and genetic material.Hanna, Tammisto, Kati, Karvonen
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Proteomics in gram‐negative bacterial outer membrane vesicles
Mass Spectrometry Reviews, 2008AbstractGram‐negative bacteria constitutively secrete outer membrane vesicles (OMVs) into the extracellular milieu. Recent research in this area has revealed that OMVs may act as intercellular communicasomes in polyspecies communities by enhancing bacterial survival and pathogenesis in hosts.
Lee, EY, Choi, DS, Kim, KP, Gho, YS
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Isolation of Outer Membrane Vesicles from Helicobacter pylori
2021Outer membrane vesicles (OMV) shed by pathogenic bacteria have multifunctional roles in disease initiation and progression. Further, their efficacy as novel vaccines has underscored their importance as potential therapeutics. Consequently, to advance allied research related to their immunogenicity and pathogenicity it is important to separate these ...
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Outer membrane vesicles as acellular vaccine against pertussis
Vaccine, 2008In this study the development and evaluation of outer membrane vesicles (OMVs) obtained from Bordetella pertussis as vaccines against pertussis disease is described. SDS-PAGE, immunoblot techniques and gel electrophoresis associated to tandem mass spectrometry were used to describe the composition of the OMVs obtained from B.
Roy, Roberts +7 more
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Outer Membrane Vesicles: Physiological Medical Applications
2012Outer membrane vesicles (OMVs) produced by Gram-negative bacteria exhibit enormous functional diversity depending on the bacterial species and environmental niche: these have enabled various physiological roles for these vesicles to play and at the same time OMVs have found important medical applications.
S. N. Chatterjee, Keya Chaudhuri
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Bacterial bioreactors: Outer membrane vesicles for enzyme encapsulation
2019Bacterial membrane vesicles, whether naturally occurring or engineered for enhanced functionality, have significant potential as tools for bioremediation, enzyme catalysis, and the development of therapeutics such as vaccines and adjuvants. In many instances, the vesicles themselves and the naturally occurring proteins are sufficient to lend ...
Kendrick B, Turner +2 more
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Outer membrane vesicles from Neisseria meningitidis.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 2002Flow cytometry was used to study the expression of leukocyte adhesion molecules CD11a, CD11b, CD11c, CD14, and CD62L (L-selectin) and production of reactive oxygen species (ROS) in an ex vivo human whole-blood system stimulated with lipopolysaccharide-containing outer membrane vesicles (LPS-OMV) from N. meningitidis.
Mohammad Reza, Mirlashari +3 more
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The “hole” story of predatory outer-membrane vesicles
Canadian Journal of Microbiology, 2018All Gram-negative bacteria release membrane vesicles. These vesicles contain a cargo of proteins and enzymes that include one or more autolysins. Autolysins are a group of enzymes with specificity for the different linkages within peptidoglycan sacculi that if uncontrolled cause bacteriolysis.
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Outer Membrane Protein Vesicle Vaccines for Meningococcal Disease
2003Alternative strategies exist for prevention of group B Neisseria meningitidis (meningococcal) disease through vaccination (see Chapters 5 , 8 , 13 , 14 in this volume). However, the most promising approach to date has been the use of outer-membrane vesicle (OMV) vaccines for induction of bactericidal antibodies against cell-surface outer-membrane ...
C E, Frasch +4 more
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Outer membrane vesicles in "Bordetella petrii"
2013Gram-negative Bakterien geben während ihres Wachstums spezielle Vesikel, die als Outer Membran Vesicles (OMVs) oder Membran-Vesicle-like Particles bezeichnet werden, ab. Diese Arbeit befasst sich mit den OMVs, welche vom Bakterium Bordetella petrii abgegeben werden, und zwar mit besonderem Fokus auf die Zeitspanne, in der die Partikel-Abgabe beginnt ...
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