Results 91 to 100 of about 521,903 (288)

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

IRIS Observations of the Low-atmosphere Counterparts of Active Region Outflows [PDF]

, 2020
Vanessa Polito, Bart de Pontieu, Paola Testa, David H. Brooks, Viggo Hansteen, Vanessa Polito, Bart de Pontieu, Paola Testa, David H. Brooks, Viggo Hansteen   +9 more
openalex   +1 more source

Identifying the outflow driving sources in Orion-KL

, 2008
The enigmatic outflows of the Orion-KL region have raised discussions about their potential driving sources for several decades. Here, we present C18O(2-1) observations combined from the Submillimeter Array and the IRAM30m telescope. The molecular gas is
Beuther, H., Nissen, H. D.
core   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source

Bimatoprost Effects on Aqueous Humor Dynamics in Monkeys

Journal of Ophthalmology, 2010
The effects of bimatoprost on aqueous humor dynamics were quantified in monkey eyes. Uveoscleral outflow was measured by the anterior chamber perfusion method, using FITC-dextran.
David F. Woodward, Achim H.-P. Krauss, Siv F. E. Nilsson   +2 more
doaj   +1 more source

Supergalactic winds driven by multiple superstar clusters

, 2003
We present two dimensional hydrodynamic calculations of free expanding supergalactic winds, taking into consideration strong radiative cooling. Our main premise is that supergalactic winds are powered by collections of superstar clusters.
Casiana Munoz‐Tunon, Guillermo Tenorio‐Tagle, Ho L. C., Larsen S. S., Maeder A., Pilyugin I. S., Sergiy Silich, Strickland D. K.   +7 more
core   +2 more sources

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Plasma Glial Fibrillary Acidic Protein Correlates With Brain Metal Burden in Wilson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuroinflammation driven by extracellular copper contributes to neuronal damage in Wilson's disease (WD). This study investigated the relationship between brain metal burden and peripheral neuroinflammation markers in WD. Methods We conducted a cross‐sectional study involving 89 participants, including patients with WD (n = 63 ...
Sung‐Pin Fan, Ya‐Fang Chen, Cheng‐Hsuan Li, Yih‐Chih Kuo, Ni‐Chung Lee, Yin‐Hsiu Chien, Wuh‐Liang Hwu, Tai‐Chung Tseng, Tung‐Hung Su, Chien‐Ting Hsu, Huey‐Ling Chen, Chin‐Hsien Lin, Yen‐Hsuan Ni   +12 more
wiley   +1 more source

Neutron-loaded outflows in gamma-ray bursts

, 2005
Relativistic neutron-loaded outflows in gamma-ray bursts are studied at their early stages, before deceleration by a surrounding medium. The outflow has four components: radiation, electrons, protons and neutrons.
Andrei M. Beloborodov, Bahcall, Beloborodov, Beloborodov, Beloborodov, Beloborodov, Daum, Derishev, Derishev, Elena M. Rossi, Fuller, Ghirlanda, Lemoine, MacFadyen, Martin J. Rees, Misner, Mészáros, Mészáros, Piran, Pruet, Rees, Ryde, Shimizu, Stepney, Svensson, Vlahakis   +25 more
core   +1 more source

Exosome Proteomics of SOD1D90A Mutation Suggest Early Disease Mechanisms, and FN1 as a Biomarker

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis (ALS) is a neuromuscular disease. Super oxide dismutase 1 (SOD1) gene mutations cause ALS, and the D90A mutation is associated with primarily upper motor neuron (UMN) loss. Objective Our goal is to reveal the early cellular events in ALS pathology and identify potential pharmacokinetic biomarkers, using well ...
Mukesh Gautam, Ali Laith, Aslihan Gunel, Melda Yilmaz, Nazli Basak, Halil Idrisoglu, P. Hande Ozdinler   +6 more
wiley   +1 more source