Results 41 to 50 of about 521,903 (288)

Mitochondrial fatty acid oxidation is stimulated by red light irradiation

open access: yesFEBS Letters, EarlyView.
Light at different wavelengths has distinct effects on keratinocyte viability and metabolism. UVA light abrogates metabolic fluxes. Blue and green light have no effect on metabolic fluxes, while red light enhanced oxidative phosphorylation by promoting fatty acid oxidation. Keratinocytes are the primary constituents of sunlight‐exposed epidermis.
Manuel Alejandro Herrera   +4 more
wiley   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Structured outflow from a dynamo active accretion disc

open access: yes, 2002
We present an axisymmetric numerical model of a dynamo active accretion disc. If the dynamo-generated magnetic field in the disc is sufficiently strong (close to equipartition with thermal energy), a fast magneto-centrifugally driven outflow develops ...
Brandenburg, Axel   +3 more
core   +2 more sources

The zinc finger domains of PARP‐1 are selectively and potently inhibited by the Au(I)‐based drugs sodium aurothiomalate and aurothioglucose

open access: yesFEBS Letters, EarlyView.
PARP‐1 is a key enzyme in the DNA damage response, and its inhibition induces cancer cell death via synthetic lethality. Au(I)‐based drugs, such as aurothioglucose and sodium aurothiomalate, block PARP‐1's DNA‐dependent activity by targeting its zinc finger domains.
Uliana Bashtanova, Melinda Jane Duer
wiley   +1 more source

Quantification of the severity of outflow stenosis of hemodialysis fistulas with a pulse- and thrill-based scoring system

open access: yesBMC Nephrology, 2020
Background Hyper-pulsatility of hemodialysis arteriovenous fistula (AVF) is the basic physical examination finding when there is outflow stenosis. The arm elevation test can also be utilized to detect outflow stenosis.
Matt Chiung-Yu Chen   +7 more
doaj   +1 more source

Direct Imaging of a Compact Molecular Outflow from a Very Low-luminosity Object; L1521F-IRS

open access: yes, 2013
We report interferometric observations of the VeLLO L1521F-IRS, in 12CO (2-1) line emission and the 1.3 mm continuum emission, using the Submillimeter Array (SMA).
Bourke, Tyler   +2 more
core   +1 more source

Multi-phase outflows in Mkn 848 observed with SDSS-MaNGA Integral Field Spectroscopy [PDF]

open access: yes, 2019
The characterisation of galaxy-scale outflows in terms of their multi-phase nature, amount, and effects of flowing material is crucial to place constraints on models of galaxy evolution.
Brusa, Marcella   +7 more
core   +2 more sources

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

A search for 95 GHz class I methanol masers in molecular outflows

open access: yes, 2012
We have observed a sample of 288 molecular outflow sources including 123 high-mass and 165 low-mass sources to search for class I methanol masers at 95 GHz transition and to investigate relationship between outflow characteristics and class I methanol ...
Chen, Xi   +4 more
core   +1 more source

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