Results 61 to 70 of about 521,903 (288)

Avaliação do fluxo de saída do ventrículo esquerdo em gatos anestesiados submetidos ao pneumoperitônio e à posição deTrendelenburg

Arquivo Brasileiro de Medicina Veterinária e Zootecnia
RESUMO Objetivou-se avaliar os efeitos do pneumoperitônio e da posição de Trendelenburg sobre o fluxo de saída do ventrículo esquerdo em gatos anestesiados.
M.L. Magalhães, L.T. Nishimura, A.T. Souza, C.F. Magalhães, E. Mattos Júnior, C.S. Honsho, D. Paulino Júnior   +6 more
doaj   +1 more source

Left Ventricular Outflow Tract Anomalies: Echocardiographic Evaluation

Journal of the Indian Academy of Echocardiography & Cardiovascular Imaging, 2020
The left ventricular outflow is divided into subvalvar area, the aortic valve and supra valvar region. There can occur a number of anomalies in the outflow tract, most commonly of which are obstructive lesions, which can exist in isolation or as a part ...
Tanuja Karande
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

THE NORTHERN TERRITORIES OF WESTERN SIBERIA: DEMOGRAPHIC TRENDS AND GROWTH PARADOXES

Север и рынок: формирование экономического порядка
This paper analyzes socio-demographic trends over the past sixty years in the northern territories of Western Siberia, specifically the Khanty-Mansiysk and Yamalo-Nenets Autonomous Okrugs. The study spans from the initial development of mineral resources
Andrei G. Shelomentsev, Vladimir M. Kurikov, Kseniya S. Goncharova, Alina V. Istratii   +3 more
doaj   +1 more source

Evidence of strong quasar feedback in the early Universe [PDF]

, 2012
Most theoretical models invoke quasar driven outflows to quench star formation in massive galaxies, this feedback mechanism is required to account for the population of old and passive galaxies observed in the local universe.
A. Ferrara, Aalto, Alatalo, Alexander, Beelen, Bertoldi, Bertoldi, Bower, C. Cicone, C. Feruglio, Cano-Díaz, Cicone, Cimatti, Croton, D. Lutz, Di Matteo, E. Piconcelli, E. Sturm, F. Fiore, F. Walter, Fabian, Fan, Farrah, Feruglio, Fischer, Glazebrook, Granato, Greene, Hailey-Dunsheath, Harrison, Hopkins, Hopkins, King, King, Komatsu, L. J. Tacconi, Lapi, Maiolino, Maiolino, Maiolino, Martin, McCarthy, Menci, Narayanan, Nesvadba, Nesvadba, Page, R. Genzel, R. Maiolino, R. Neri, Rupke, S. Gallerani, Saracco, Savage, Silk, Springel, Sturm, Thacker, Valiante, Veilleux, Walter, Walter, Walter, Weiß, Wilson, Zubovas   +65 more
core   +2 more sources

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Multi-objective optimization to manage reservoir water quality and quantity via selective withdrawal and watershed control [PDF]

Sustainable Earth Trends, 2022
A new approach was presented to manage simultaneously reservoir outflow quantity and quality. Two strategies were used to control reservoir outflow quality: (1) reservoir inflow control with Best Management Practices (BMPs) in the watershed and (2 ...
Habib Abbasi, Mohammad taghi Aalami, Mohammad Hossein Niksokhan, Leila Malekan   +3 more
doaj  

A molecular-line study of the interstellar bullet engine IRAS 05506+2414

, 2017
We present interferometric and single-dish molecular line observations of the interstellar bullet-outflow source IRAS 05506+2414, whose wide-angle bullet spray is similar to the Orion BN/KL explosive outflow and likely arises from an entirely different ...
Claussen, Mark, Contreras, Carmen Sanchez, Lee, Chin-Fei, Morris, Mark R., Patel, Nimesh, Sahai, Raghvendra   +5 more
core   +1 more source

SMA outflow/disk studies in the massive star-forming region IRAS18089-1732 [PDF]

, 2004
SMA observations of the massive star-forming region IRAS 18089-1732 in the 1mm and 850mu band reveal outflow and disk signatures in different molecular lines. The SiO(5--4) data show a collimated outflow in the northern direction.
Beuther, H., Ho, P. T. P., Hunter, T. R., Lim, J., Liu, S. -Y., Ohashi, N., Sollins, P., Sridharan, T. K., Su, Y. N., Zhang, Q., Zhao, J. -H.   +10 more
core   +1 more source

Characterizing epithelial‐mesenchymal transition‐linked heterogeneity in breast cancer circulating tumor cells at a single‐cell level

Molecular Oncology, EarlyView.
In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa, Julia Richert, Tomasz Stokowy, Alicja Staśczak, Mariusz Szajewski, Maciej Ciesielski, Petra M. Grešner, Bartłomiej Tomasik, Łukasz Arcimowicz, Agnieszka Stankiewicz, Grażyna Suchodolska, Elżbieta Senkus, Wiesław Kruszewski, Anna J. Żaczek, Aleksandra Markiewicz   +14 more
wiley   +1 more source