Results 61 to 70 of about 168,432 (316)
Multi-objective optimization to manage reservoir water quality and quantity via selective withdrawal and watershed control [PDF]
Sustainable Earth Trends, 2022 A new approach was presented to manage simultaneously reservoir outflow quantity and quality. Two strategies were used to control reservoir outflow quality: (1) reservoir inflow control with Best Management Practices (BMPs) in the watershed and (2 ...
Habib Abbasi +3 more
doaj
Molecular Oncology, EarlyView.This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima +6 more
wiley +1 more source
Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs
Molecular Oncology, EarlyView.In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza +3 more
wiley +1 more source
X-Ray Properties of NGC 253's Starburst-driven Outflow
The Astrophysical Journal, 2023 We analyze image and spectral data from ≈365 ks of observations from the Chandra X-ray Observatory of the nearby, edge-on starburst galaxy NGC 253 to constrain properties of the hot phase of the outflow.
Sebastian Lopez +7 more
doaj +1 more source
FEBS Open Bio, EarlyView.The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik +3 more
wiley +1 more source
Meteorological factors controlling low-level continental pollutant outflow across a coast [PDF]
Atmospheric Chemistry and Physics, 2014 Coastal outflow describes the horizontal advection of pollutants from the continental boundary layer (BL) across a coastline. The outflow can ventilate polluted continental BLs and thus regulate air quality in highly populated coastal regions. This paper
D. L. Peake +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna +4 more
wiley +1 more source
THE NORTHERN TERRITORIES OF WESTERN SIBERIA: DEMOGRAPHIC TRENDS AND GROWTH PARADOXES
Север и рынок: формирование экономического порядкаThis paper analyzes socio-demographic trends over the past sixty years in the northern territories of Western Siberia, specifically the Khanty-Mansiysk and Yamalo-Nenets Autonomous Okrugs. The study spans from the initial development of mineral resources
Andrei G. Shelomentsev +3 more
doaj +1 more source
THE COMPLETE SURVEY OF OUTFLOWS IN PERSEUS [PDF]
The Astrophysical Journal, 2010 We present a study on the impact of molecular outflows in the Perseus molecular cloud complex using the COMPLETE survey large-scale 12CO(1-0) and 13CO(1-0) maps. We used three-dimensional isosurface models generated in RA-DEC-Velocity space to visualize the maps.
Michael Halle +5 more
openaire +6 more sources
Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies
FEBS Open Bio, EarlyView.Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa +13 more
wiley +1 more source