Results 71 to 80 of about 531,231 (335)
Measurement of Outflow Facility Using iPerfusion. [PDF]
PLoS ONE, 2016 Elevated intraocular pressure (IOP) is the predominant risk factor for glaucoma, and reducing IOP is the only successful strategy to prevent further glaucomatous vision loss.
Joseph M Sherwood +4 more
doaj +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Arquivo Brasileiro de Medicina Veterinária e ZootecniaRESUMO Objetivou-se avaliar os efeitos do pneumoperitônio e da posição de Trendelenburg sobre o fluxo de saída do ventrículo esquerdo em gatos anestesiados.
M.L. Magalhães +6 more
doaj +1 more source
Left Ventricular Outflow Tract Anomalies: Echocardiographic Evaluation
Journal of the Indian Academy of Echocardiography & Cardiovascular Imaging, 2020 The left ventricular outflow is divided into subvalvar area, the aortic valve and supra valvar region. There can occur a number of anomalies in the outflow tract, most commonly of which are obstructive lesions, which can exist in isolation or as a part ...
Tanuja Karande
doaj +1 more source
Direct Imaging of a Compact Molecular Outflow from a Very Low-luminosity Object; L1521F-IRS
, 2013 We report interferometric observations of the VeLLO L1521F-IRS, in 12CO (2-1) line emission and the 1.3 mm continuum emission, using the Submillimeter Array (SMA).
Bourke, Tyler +2 more
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Multi-objective optimization to manage reservoir water quality and quantity via selective withdrawal and watershed control [PDF]
Sustainable Earth Trends, 2022 A new approach was presented to manage simultaneously reservoir outflow quantity and quality. Two strategies were used to control reservoir outflow quality: (1) reservoir inflow control with Best Management Practices (BMPs) in the watershed and (2 ...
Habib Abbasi +3 more
doaj
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Matrix Metalloproteinases and Glaucoma Treatment. [PDF]
, 2020 Matrix metalloproteinases (MMPs) are a family of proteolytic enzymes that degrade extracellular matrix (ECM) components such as collagen and have important roles in multiple biological processes, including development and tissue remodeling, both in ...
Dibas, Mohammed +3 more
core
Steady General Relativistic Magnetohydrodynamic Inflow/Outflow Solution along Large-Scale Magnetic Fields that Thread a Rotating Black Hole [PDF]
, 2015 General relativistic magnetohydrodynamic (GRMHD) flows along magnetic fields threading a black hole can be divided into inflow and outflow parts, according to the result of the competition between the black hole gravity and magneto-centrifugal forces ...
Asada, Keiichi +5 more
core +2 more sources