Results 81 to 90 of about 531,231 (335)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

A New Machine Learning Algorithm to Simulate the Outlet Flow in a Reservoir, Based on a Water Balance Model

Limnological Review
Predicting water losses and final storage in reservoirs has become increasingly relevant in the efficient control and optimization of water provided to agriculture, livestock, industry, and domestic consumption, aiming to mitigate the risks associated ...
Marco Antonio Cordero Mancilla, Wilmer Moncada, Vinie Lee Silva Alvarado   +2 more
doaj   +1 more source

Protostellar Jets Enclosed by Low-velocity Outflows

, 2014
A protostellar jet and outflow are calculated for \sim 270 yr following the protostar formation using a three dimensional magnetohydrodynamics simulation, in which both the protostar and its parent cloud are spatially resolved. A high-velocity (\sim100km/
Machida, Masahiro N.
core   +1 more source

SMA outflow/disk studies in the massive star-forming region IRAS18089-1732 [PDF]

, 2004
SMA observations of the massive star-forming region IRAS 18089-1732 in the 1mm and 850mu band reveal outflow and disk signatures in different molecular lines. The SiO(5--4) data show a collimated outflow in the northern direction.
Beuther, H., Ho, P. T. P., Hunter, T. R., Lim, J., Liu, S. -Y., Ohashi, N., Sollins, P., Sridharan, T. K., Su, Y. N., Zhang, Q., Zhao, J. -H.   +10 more
core   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

THE NORTHERN TERRITORIES OF WESTERN SIBERIA: DEMOGRAPHIC TRENDS AND GROWTH PARADOXES

Север и рынок: формирование экономического порядка
This paper analyzes socio-demographic trends over the past sixty years in the northern territories of Western Siberia, specifically the Khanty-Mansiysk and Yamalo-Nenets Autonomous Okrugs. The study spans from the initial development of mineral resources
Andrei G. Shelomentsev, Vladimir M. Kurikov, Kseniya S. Goncharova, Alina V. Istratii   +3 more
doaj   +1 more source

Who Is Eating the Outflow?: High-Angular Resolution Study of an Intermediate-Mass Protostar in L1206

, 2006
Up to now only a few intermediate-mass molecular outflows have been studied with enough high-angular resolution. The aim of this work is to study in detail the intermediate-mass YSO IRAS 22272+6358A, which is embedded in L1206, and its molecular outflow,
André, Arce, Bachiller, Bachiller, Bachiller, Beltrán, Beltrán, Beltrán, Bontemps, Cabrit, Casoli, Chernin, Chung, Curiel, Curiel, de Vicente, Frerking, Fuente, Gueth, Gueth, Hasegawa, Hogerheijde, Hogerheijde, J. M. Girart, Jørgensen, Kulesa, Kutner, Lee, Lee, Looney, M. T. Beltrán, MacLaren, MacLeod, Martín-Pintado, McCutcheon, Molinari, Ossenkopf, Palla, Pezzuto, R. Estalella, Ressler, Richards, Richer, Ridge, Rizzo, Scoville, Scoville, Shepherd, Snell, Sridharan, Stanke, Sugitani, Sugitani, Sugitani, Vanden Bout, Wilking, Williams, Wouterloot, Wu, Zhang   +59 more
core   +1 more source

Nucleosynthesis in the Outflow from Gamma Ray Burst Accretion Disks [PDF]

, 2005
We examine the nucleosynthesis products that are produced in the outflow from rapidly accreting disks. We find that the type of element synthesis varies dramatically with the degree of neutrino trapping in the disk and therefore the accretion rate of the
G. C. McLaughlin, McLaughlin G. C., R. Surman, Ruffert M., W. R. Hix   +4 more
core   +1 more source

Characterizing outflows in the Cygnus X region [PDF]

, 2021
Soumen Deb, R. Kothes, Erik Rosolowsky
openalex   +1 more source

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

FEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh, Éva Bozó, Zikrullah Bölükkaya, Artem Zhyvolozhnyi, Anatoliy Samoylenko, Henrikki Liimatainen, Seppo J. Vainio, Caglar Elbuken   +7 more
wiley   +1 more source