Results 91 to 100 of about 324,246 (376)

NIHAO - XI. Formation of ultra-diffuse galaxies by outflows [PDF]

open access: yes, 2016
We address the origin of Ultra-Diffuse Galaxies (UDGs), which have stellar masses typical of dwarf galaxies but effective radii of Milky Way-sized objects. Their formation mechanism, and whether they are failed $\rm L_{\star}$ galaxies or diffuse dwarfs,
A. Cintio   +5 more
semanticscholar   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Nucleosynthesis in Outflows from the Inner Regions of Collapsars

open access: yes, 2003
We consider nucleosynthesis in outflows originating from the inner regions of viscous accretion disks formed after the collapse of a rotating massive star.
Balbus S. A.   +7 more
core   +2 more sources

SMA observations of the proto brown dwarf candidate SSTB213 J041757 [PDF]

open access: yes, 2014
Context. The previously identified source SSTB213 J041757 is a proto brown dwarf candidate in Taurus, which has two possible components A and B. It was found that component B is probably a class 0/I proto brown dwarf associated with an extended envelope.
C. -f. Lee   +4 more
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Determinants of Net Capital Expenditure Cash Outflows: Evidence from the Pharmaceutical Sector of Bangladesh

open access: yesAsian Journal of Accounting Perspectives, 2017
This study attempts to identify the key determinants of net capital expenditure outflows for a panel of 14 listed pharmaceutical companies. The study has used data from 2003-2015 for each company.
Md. Thasinul Abedin   +2 more
doaj   +5 more sources

Global dynamics of advection-dominated accretion flows with magnetically driven outflow

open access: yes, 2009
We study the global dynamics of advection-dominated accretion flows (ADAFs) with magnetically driven outflows. A fraction of gases in the accretion flow is accelerated into the outflows, which leads to decreasing of the mass accretion rate in the ...
Armitage   +49 more
core   +1 more source

Delayed or No Feedback? Gas Outflows in Type 2 AGNs. III. [PDF]

open access: yes, 2017
We present gas kinematics based on the [O iii]λ5007 line and their connection to galaxy gravitational potential, active galactic nucleus (AGN) energetics, and star formation, using a large sample of ∼110,000 AGNs and star-forming (SF) galaxies at z < 0.3.
J. Woo, D. Son, Hyun-Jin Bae
semanticscholar   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Limits on luminosity and mass accretion rate of a radiation pressure dominated accretion disc

open access: yes, 2015
There is a maximum for the gravity of a black hole in the vertical direction in the accretion disc. Outflows may probably be driven from the disc if the radiation flux of the disc is greater than a critical value corresponding to the maximal vertical ...
Cao, Xinwu, Gu, Wei-Min
core   +1 more source

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