Results 71 to 80 of about 305,999 (243)
Quantifying Supernovae-driven Multiphase Galactic Outflows [PDF]
, 2016 Galactic outflows are observed everywhere in star-forming disk galaxies and are critical for galaxy formation. Supernovae (SNe) play the key role in driving the outflows, but there is no consensus as to how much energy, mass, and metal they can launch ...
M. Li 李, G. Bryan, J. Ostriker
semanticscholar +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Molecular Outflows in Local ULIRGs: Energetics from Multitransition OH Analysis [PDF]
, 2016 We report on the energetics of molecular outflows in 14 local ultraluminous infrared galaxies (ULIRGs) that show unambiguous outflow signatures (P Cygni profiles or high-velocity absorption wings) in the far-infrared lines of OH measured with the ...
E. González-Alfonso +15 more
semanticscholar +1 more source
Proceedings of the International Astronomical Union, 2005 To be published in the IAU Symposium 227 conference proceedings: Massive Star Birth: A Crossroads of Astrophysics See http://www.aoc.nrao.edu/~dshepher/science.shtml for a ...
openaire +2 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
, 2017 We apply an analytic Markov Chain Monte Carlo model to a sample of 18 AGN-driven biconical outflows that we identified from a sample of active galaxies with double-peaked narrow emission lines at z < 0.1 in the Sloan Digital Sky Survey. We find that 8/18
Barrows, R. Scott +4 more
core +1 more source
The SILCC project - III. Regulation of star formation and outflows by stellar winds and supernovae [PDF]
, 2016 We study the impact of stellar winds and supernovae on the multiphase interstellar medium using three-dimensional hydrodynamical simulations carried out with FLASH. The selected galactic disc region has a size of (500 pc)(2) x +/- 5 kpc and a gas surface
A. Gatto +11 more
semanticscholar +1 more source
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
, 2010 Persistent outflows have recently been detected at boundaries of some active regions. Although these outflows are suggested to be possible sources of the slow solar wind, the nature of these outflows is poorly understood.
Baker +14 more
core +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source