Results 51 to 60 of about 304,299 (338)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

A Filtering-Based Approach for Improving Crowdsourced GNSS Traces in a Data Update Context

open access: yesISPRS International Journal of Geo-Information, 2019
Traces collected by citizens using GNSS (Global Navigation Satellite System) devices during sports activities such as running, hiking or biking are now widely available through different sport-oriented collaborative websites.
Stefan S. Ivanovic   +3 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

OUTLIER DETECTION TECHNIQUE USING CT-OCSVM AND FUZZY RULE-BASED SYSTEM IN WIRELESS SENSOR NETWORKS

open access: yesJournal of Engineering and Sustainable Development, 2020
The development of Wireless Sensor Networks (WSNs) has been attained in the past few years due to its important using in wide range of application. The readings of data derived from WSN nodes are not always accurate and may contain abnormal data.
Hussein Hassan Shia   +2 more
doaj  

A Novel Outlier Immune Multipath Fingerprinting Model for Indoor Single-Site Localization

open access: yesIEEE Access, 2019
Multipath fingerprinting is a promising indoor location technique, which contains abundant position features of the received array signals. Effectively representing the position information is one critical issue in fingerprinting localization. Meanwhile,
Limin Chen   +3 more
doaj   +1 more source

TreeShrink: fast and accurate detection of outlier long branches in collections of phylogenetic trees

open access: yesBMC Genomics, 2018
Sequence data used in reconstructing phylogenetic trees may include various sources of error. Typically errors are detected at the sequence level, but when missed, the erroneous sequences often appear as unexpectedly long branches in the inferred ...
U. Mai, S. Mirarab
semanticscholar   +1 more source

Learning Representations of Ultrahigh-dimensional Data for Random Distance-based Outlier Detection [PDF]

open access: yesKnowledge Discovery and Data Mining, 2018
Learning expressive low-dimensional representations of ultrahigh-dimensional data, e.g., data with thousands/millions of features, has been a major way to enable learning methods to address the curse of dimensionality.
Guansong Pang   +3 more
semanticscholar   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Outliers Detection Models in Shewhart Control Charts; an Application in Photolithography: A Semiconductor Manufacturing Industry

open access: yesMathematics, 2020
Shewhart control charts with estimated control limits are widely used in practice. However, the estimated control limits are often affected by phase-I estimation errors.
Ishaq Adeyanju Raji   +4 more
doaj   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

open access: yesFEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul   +3 more
wiley   +1 more source

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