Results 61 to 70 of about 245,542 (303)
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta +7 more
wiley +1 more source
Middle-Upper Jurassic palynology of the Sagres region and the Carrapateira outlier: southern Portugal [PDF]
, 2014 The palynology of the Middle-Upper Jurassic fill of the Sagres region (Algarve Basin) and the Carrapateira outlier, southern Portugal was investigated. Samples were collected from Mareta beach, Cilheta beach and the Carrapateira outlier.
Riding, Jim +3 more
core +1 more source
Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank
FEBS Open Bio, EarlyView.Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer +7 more
wiley +1 more source
IEEE Access, 2018 The cardinality-balanced multi-target multi-Bernoulli (CBMeMBer) filter is a promising solution for multi-target tracking. However, the performance of the CBMeMBer filter will be degraded severely by outliers in the presence of heavy-tailed process noise
Mingjie Wang +3 more
doaj +1 more source
Journal of the American College of Cardiology, 2009 ![Figure][1] Physicians have always been proud of their achievements, justifiably so I think. We have successfully competed for positions in the best colleges, admission to medical school, and appointments to the finest training programs.
openaire +2 more sources
FEBS Open Bio, EarlyView.In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
A New Acoustic Emission Source Location Method Using Tri-Variate Kernel Density Estimator
IEEE Access, 2019 A new AE location method using tri-variate kernel density estimator is developed in this paper. Firstly, combinations of every six arrivals are obtained from a multi-sensor location system, and the preliminary location results are obtained by solving the
Zilong Zhou +6 more
doaj +1 more source
Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi +8 more
wiley +1 more source