Results 51 to 60 of about 245,542 (303)
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
Outlier robust small area estimation
, 2011 Recently proposed outlier robust small area estimators can be substantially biased when outliers are drawn from a distribution that has a different mean from that of the rest of the survey data.
Chandra, Hukum +3 more
core +1 more source
A Distributed Solution for Privacy Preserving Outlier Detection [PDF]
, 2011 In this paper, we study some parties - each has a private data set - want to conduct the outlier detection on their joint data set, but none of them want to disclose its private data to the other parties.
Luong, The Dung, Ho, Tu Bao
core +1 more source
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Effect of terahertz irradiation on DNA damage repair in living cells
FEBS Open Bio, EarlyView.We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno +3 more
wiley +1 more source
A variance shilf model for outlier detection and estimation in linear and linear mixed models [PDF]
, 2008 Includes abstract.Includes bibliographical references.Outliers are data observations that fall outside the usual conditional ranges of the response data.They are common in experimental research data, for example, due to transcription errors or faulty ...
Gumedze, Freedom Nkhululeko
core +1 more source
FEBS Open Bio, EarlyView.KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph +7 more
wiley +1 more source
Unsupervised Outlier Profile Analysis
, 2014 In much of the analysis of high-throughput genomic data, “interesting” genes have been selected based on assessment of differential expression between two groups or generalizations thereof.
Song Li, Debashis Ghosh
core +1 more source
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
FEBS Open Bio, EarlyView.Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
Outlier detection in video sequences under affine projection [PDF]
, 2001 A novel robust method for outlier detection in structure and motion recovery for affine cameras is presented. It is an extension of the well-known Tomasi-Kanade factorization technique (C. Tomasi T. Kanade, 1992) designed to handle outliers.
Heyden, A., Huynh, D.Q.
core