Results 31 to 40 of about 364,272 (265)

A Feature-Cascaded Correntropy LSTM for Tourists Prediction

IEEE Access, 2021
Forecasting the number of tourists is significant to public safety, which can enable the government to control the sudden influx of tourists timely. The temporal dependence (closeness and period), external factors such as holidays, government policy, as ...
Yuehai Chen, Jing Yang, Kun Zhang, Yi Xu, Yuewen Liu   +4 more
doaj   +1 more source

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro, Freda Qi, Karen Colwill, Alina D. Dorogy, Ying Liu, Michelle Science, Anne‐Claude Gingras, James M. Rini, Sumit Gupta, Sarah Alexander, Shelly Bolotin, Tania H. Watts   +11 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

A Flexible Smoother Adapted to Censored Data With Outliers and Its Application to SARS-CoV-2 Monitoring in Wastewater

Frontiers in Applied Mathematics and Statistics, 2022
A sentinel network, Obépine, has been designed to monitor SARS-CoV-2 viral load in wastewaters arriving at wastewater treatment plants (WWTPs) in France as an indirect macro-epidemiological parameter.
Marie Courbariaux, Nicolas Cluzel, Siyun Wang, Vincent Maréchal, Laurent Moulin, Sébastien Wurtzer, Obépine Consortium, Jean-Marie Mouchel, Yvon Maday, Grégory Nuel, Grégory Nuel, Isabelle Bertrand, Mickaēl Boni, Christophe Gantzer, Soizick F. Le Guyader, Yvon Maday, Vincent Maréchal, Jean-Marie Mouchel, Laurent Moulin, Rémy Teyssou, Sébastien Wurtzer   +20 more
doaj   +1 more source

Once an Outlier, Still an Outlier?

International Journal of Business & Economics (IJBE), 2020
Japan’s financial market is very interesting. It is widely documented that, while cross-sectional momentum exists in many countries, it does not exist in Japan. Recently, time series momentum has been dubbed, yet there is little research on its performance in Japan.
openaire   +2 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Sensing Accuracy Enhancement of Phase-Sensitive Optical Frequency Domain Reflectometry Using Hybrid Hampel-Median Filter

IEEE Photonics Journal
We propose a novel filter scheme to enhance the sensing accuracy of phase-sensitive optical frequency domain reflectometer (Φ-OFDR) while maintaining high spatial resolution via cascading Hampel filter and median filter.
Yiheng Cheng, Qinlin Zeng, Fei Liu, Fei Cui, Zhi Wang, Dan Li, Benzhang Wang, Xian Zhou   +7 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Handling Multicollinearity and Outliers in Logistic Regression Using the Robust Kibria–Lukman Estimator

Axioms
Logistic regression models encounter challenges with correlated predictors and influential outliers. This study integrates robust estimators, including the Bianco–Yohai estimator (BY) and conditionally unbiased bounded influence estimator (CE), with the ...
Adewale F. Lukman, Suleiman Mohammed, Olalekan Olaluwoye, Rasha A. Farghali   +3 more
doaj   +1 more source