Results 41 to 50 of about 364,272 (265)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Nonlinear Regressive Maximum Correntropy Extended Kalman Filter With Student’s t-Kernel for GPS Navigation

IEEE Access
State estimation is a critical task across many disciplines, with the extended Kalman filter (EKF) being a widely adopted solution. However, the EKF is built on the mean square error criterion, which limits it to capturing only second-order noise ...
Amita Biswal, Dah-Jing Jwo
doaj   +1 more source

A influência de outliers nos estudos métricos da informação: uma análise de dados univariados

Em Questão, 2018
Este artigo apresenta uma nova fórmula de detecção de outliers via Análise Exploratória de Dados, levando em conta a assimetria dos dados, e também estuda o efeito da remoção dos outliers dos dados originais.
Luís Fernando Maia Lima, Alexandre Masson Maroldi, Dávilla Vieira Odízio da Silva, Carlos Roberto Massao Hayashi, Maria Cristina Piumbato Innocentini Hayashi   +4 more
doaj   +1 more source

Physicians as Outliers

Journal of the American College of Cardiology, 2009
![Figure][1] Physicians have always been proud of their achievements, justifiably so I think. We have successfully competed for positions in the best colleges, admission to medical school, and appointments to the finest training programs.
openaire   +2 more sources

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Research on Interval Probability Prediction and Optimization of Vegetation Productivity in Hetao Irrigation District Based on Improved TCLA Model

Agronomy
Vegetation productivity, as an essential global carbon sink, directly influences the variety and stability of ecosystems. Precise vegetation productivity monitoring and forecasting are crucial for the global carbon cycle.
Jie Ren, Delong Tian, Hexiang Zheng, Guoshuai Wang, Zekun Li   +4 more
doaj   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Araştırmalarda Uygun İstatistiksel Tekniğin Belirlenmesinde Normallik ve Homojenlik İhlallerinin Etkisinin İlgili Literatür Bağlamında Değerlendirilmesi

Journal of Psychometric Research
Araştırmalarda uygun istatistiksel tekniğin belirlenmesi, araştırmanın metodolojik tasarımının yanı sıra analizin amacı, örneklem büyüklüğü ve yapısı, verilerin ve veri setinin karakteristiğinin de dikkate alınmasını gerektiren zorlayıcı bir aşamadır ...
İrem Çelik, Sibel Urlu, Ergul Demir
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source