Results 51 to 60 of about 123,753 (267)

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Disparity Map Generation from Illumination Variant Stereo Images Using Efficient Hierarchical Dynamic Programming

The Scientific World Journal, 2014
A novel hierarchical stereo matching algorithm is presented which gives disparity map as output from illumination variant stereo pair. Illumination difference between two stereo images can lead to undesirable output.
Viral H. Borisagar, Mukesh A. Zaveri
doaj   +1 more source

Output-sensitive modular algorithms for polynomial matrix normal forms

Journal of Symbolic Computation, 2007
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Cheng, Howard, Labahn, George
openaire   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

A new algorithm for computing visibility graphs of polygonal obstacles in the plane

Journal of Computational Geometry, 2015
Given a set of $h$ pairwise disjoint polygonal obstacles with a total of $n$ vertices in the plane, the vertex-vertex visibility graph is an undirected graph whose nodes are vertices of the obstacles and whose edges are pairs of visible vertices.
Danny Z. Chen, Haitao Wang
doaj   +1 more source

Output-sensitive algorithm for the edge-width of an embedded graph [PDF]

Proceedings of the twenty-sixth annual symposium on Computational geometry, 2010
Let G be an unweighted graph of complexity n cellularly embedded in a surface (orientable or not) of genus g. We describe improved algorithms to compute (the length of) a shortest non-contractible and a shortest non-separating cycle of G. If k is an integer, we can compute such a non-trivial cycle with length at most k in O(gnk) time, or correctly ...
Sergio Cabello, Éric Colin de Verdière, Francis Lazarus   +2 more
openaire   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gabor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Vehicle classification algorithm based on binary proximity sensors and neural networks

Tongxin xuebao, 2008
To improve the classification accuracy, a new algorithm was developed with binary proximity magnetic sen- sors and back propagation neural networks. In this algorithm, use the low cost and high sensitive magnetic sensors to de- tect the magnetic field ...
ZHANG Wei, TAN Guo-zhen, DING Nan, SHANG Yao   +3 more
doaj   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source