Results 141 to 150 of about 2,643,650 (314)

Understanding Language Learning: Review of the Application of the Interaction Model in Foreign Language Contexts

open access: yesMalaysian Journal of Learning and Instruction, 2014
Purpose â€“ This paper examined the application of the inputinteraction-output model in English-as-Foreign-Language (EFL) learning environments with four specific questions: (1) How do the three components function in the model?
L. Quentin Dixon, Shuang Wu
doaj  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

The Output-Inflation Trade-off in African Less Developed Countries [PDF]

open access: yes
This paper investigates the nature of the short-run output-inflation trade-off and policy effectiveness in African less developed countries. Using a sample of thirteen countries over the period 1960-98, cointegration and error correction modelling ...
Mark J. Holmes
core  

Robust output stability and input-to-output stability based on output dissipation

open access: yes
LaSalle techniques to ensure the convergence of a given output usually fail at guaranteeing uniform convergence time, which induces robustness issues. Recent works have provided extra conditions under which a Lyapunov function that dissipates in terms of only the output guarantees this uniformity.
Chaillet, Antoine   +2 more
openaire   +2 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Balanced Growth and Output Convergence in Europe [PDF]

open access: yes
Using OECD quarterly data on consumption, output and investment from 1980, the balanced growth hypothesis is tested country by country for seven European economies, Belgium, Finland, France, Holland, Italy, Spain and the UK. Output series for each of the
Clifford L.F. Attfield
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Propagation effects of taxes in Romania: An input-output analysis [PDF]

open access: yes
The Input-Output model (IO) is an important tool of economic analysis, providing a predictive analysis framework for economic changes, if properly used. In developing measures, strategies, etc.
GHEORGHE ZAMAN   +2 more
core  

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