Results 161 to 170 of about 2,643,650 (314)

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Estimating the output gap for the Maltese economy

open access: yes
An attempt is made in this paper to arrive at an estimate of the output gap for the Maltese economy on a quarterly and annual basis. Two approaches are adopted, namely the Hodrick-Prescott filter and the aggregate production function method, with their ...
Grech, Aaron George
core  

Tourism and Economic Development in Romania: Input-Output Analysis Perspective [PDF]

open access: yes
Tourism provides a lot of opportunities for sustainable economic development. At local level, by its triggering effect it could represent a factor of economic recovery, by putting to good use the local material and human potential.
GHEORGHE ZAMAN   +3 more
core  

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Did the Crisis Affect Potential Output? [PDF]

open access: yes
Conventional Phillips-curve models that are used to estimate the output gap detect a substantial decline in potential output due to the present crisis. Using a multivariate state space model, we show that this result does not hold if the long run role of
Makram El-Shagi
core  

Wind energy-driven rabbit hair TENG for railway detection. [PDF]

open access: yesiScience
Chen L   +5 more
europepmc   +1 more source

Scientific Output

open access: yesRevista Brasileira de Ortopedia (English Edition), 2009
openaire   +2 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

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