Results 61 to 70 of about 917,560 (312)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Three-Coil Wireless Charging System Based on S-PS Topology

Energies
To protect the battery, radio energy transmission charging typically uses constant current (CC) charging before switching to constant voltage (CV) charging to enhance battery durability.
Kai Yan, Ruirong Dang, Wenzhen Wang
doaj   +1 more source

Experimental Validation of a Marine Current Turbine Simulator: Application to a Permanent Magnet Synchronous Generator-Based System Second-Order Sliding Mode Control [PDF]

, 2011
This paper deals with the experimental validation of a Matlab-Simulink simulation tool of marine current turbine (MCT) systems. The developed simulator is intended to be used as a sizing and site evaluation tool for MCT installations.
AHMED-ALI, Tarek, BENELGHALI, Seifeddine, CHARPENTIER, Jean-Frederic, BENBOUZID, Mohamed, Jean Frédéric Charpentier, Frédéric Charpentier, Jean, Seifeddine Benelghali, Mohamed El Hachemi Benbouzid, Iulian Munteanu, Munteanu, Iulian, MANTEANU, Julian, Tarek Ahmed-Ali   +11 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

A high step-up double-dual-boost converter with continuous output current

e-Prime: Advances in Electrical Engineering, Electronics and Energy
Although recently proposed double-dual-boost (DDB) DC-DC converters can be used in various applications, they are unable to achieve a higher voltage gain than the conventional DDB converter and typically suffer from a discontinuous output current.
Mohammad Lotfi-Nejad, Amir Abbas Aghajani, Hossein Hajisadeghian, Ali Akbar Moti Birjandi, Ehsan Adib   +4 more
doaj   +1 more source

Effect of the Shape of Stator Blades on the Performance Output of a Vertical Axis Marine Current Turbine

, 2013
Due to the diminishing reserves of fossil fuels and increased pollution from exploitation of these fuels, the world is focusing on the renewable energy sources.
Ubbi, Kuldip, Asim, Taimoor, Mishra, Rakesh   +2 more
core  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source