Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Novel Current-Conveyor-Based Universal Current-Mode Biquad Filter with Three Inputs and One Output
Active and Passive Electronic Components, 1998 A novel universal current-mode filter with three inputs and one high imedance output is presented. The proposed circuit uses four plus-type second-generation current-conveyors, grounded resistors and grounded capacitors.
Muhammad Taher Abuelma'atti +1 more
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Additional Effect of High-output Current and/or High-duty Cycle in Vagus Nerve Stimulation for Adolescent/Adult Intractable Epilepsy. [PDF]
Neurol Med Chir (Tokyo), 2023 Tamura K +11 more
europepmc +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
The reliability of Canadian output gap estimates [PDF]
Recent work on policy rules under uncertainty have highlighted the impact of output gap measurement errors on economic outcomes and their importance in the formulation of appropriate policy rules.
van Norden, Simon, Cayen, Jean-Philippe
core
Fast Response GaN Nanoscale Air Channel Diodes with Highly Stable 10 mA Output Current toward Wafer-Scale Fabrication. [PDF]
Adv Sci (Weinh), 2023 Wei Y +7 more
europepmc +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Current transformer circuits for power electronics applications [PDF]
This thesis investigates the operation of the current transfonner (CT) when sensing retum-to-zero current pulses in power electronic circuitry. The CT's output signal is nonnally rectified when sensing current pulses and the effects of the different ...
McNeill, John Neville
core
Switch-Level Interleaved Converter: Circuit Operation, Output Ripple and Circulating Current
Eletrônica de PotênciaThis paper discusses an interleaved converter topology for DC-AC conversion in power electronics applications. The proposed topology leverages a switch-level interleaving technique to overcome the limitations of conventional interleaved inverters ...
Vítor H. M. Biajo +2 more
doaj +1 more source