Results 11 to 20 of about 2,273 (120)

Fuzuloparib with or without apatinib as maintenance therapy in newly diagnosed, advanced ovarian cancer (FZOCUS-1): A multicenter, randomized, double-blind, placebo-controlled phase 3 trial. [PDF]

CA Cancer J Clin
Abstract Although poly(adenosine diphosphate‐ribose) polymerase inhibitors (PARPis) and bevacizumab were approved as first‐line maintenance for advanced ovarian cancer (OC), evidence comparing this combination with PARPi monotherapy, especially in BRCA‐mutated/homologous recombination‐deficient (HRD) patients, is lacking.
Wu L, Wang J, Li Q, Wang D, Zhang C, Tang J, Zhang G, Hao M, Yao D, Gao Q, Zhang Y, An R, Yin R, Wang L, Xia B, Zhou Q, Yang H, Zhu J, Jiang K, Chen Z, Wu Q, Duan W, Huang Y, Zhang H, Wei S, Li G, Meng Y, Wang K, Yang X, Huang X, Pan L, Yu J, Lou G, Zhang Y, Zhou H, Guo X, Yang H, Cheng X, Li X, Wang W, Zhao H, Li Y, Yang Y, Lin A, Cheng W, Chen L, Xie X, Di W, Hu Y, Chen M, Wen H, Cai L, Wu X, Lin Z, Wang Q, Yang X, Li N.   +56 more
europepmc   +2 more sources

Patient involvement in research within the Gynecological Cancer InterGroup: A call to action for a systematic approach: Results from a survey

Health Science Reports, Volume 6, Issue 12, December 2023., 2023
Abstract Background and Aims Involving patients in research, not only as trial subjects, is not a newly established practice. Over the last two decades, patient roles have gradually expanded to become active research contributors, creating a more patient‐centered research landscape.
Ivana Nohová, John Andrews, Bénédicte Votan, Austin Miller, Jalid Sehouli, Regina Berger   +5 more
wiley   +1 more source

Causes of pregnancy arrest in the canine species

Reproduction in Domestic Animals, Volume 58, Issue S2, Page 72-83, September 2023., 2023
Abstract In the canine species, early pregnancy arrest before 30–40 days of pregnancy will induce intra‐uterine embryonic or foetal resorption, with very few clinical signs. If no genital examination by ultrasound is performed at that time, it will often remain unnoticed and the bitch will be qualified as infertile. It is only when pregnancy stops at a
Alain Fontbonne
wiley   +1 more source

Prospective evaluation of the tolerability and efficacy of niraparib dosing based on baseline body weight and platelet count: Results from the PRIMA/ENGOT‐OV26/GOG‐3012 trial

Cancer, Volume 129, Issue 12, Page 1846-1855, 15 June 2023., 2023
Abstract Background The PRIMA/ENGOT‐OV26/GOG‐3012 (NCT02655016) trial was amended to prospectively evaluate the safety and efficacy of an individualized starting dose (ISD) regimen of niraparib for first‐line maintenance therapy in patients with newly diagnosed advanced ovarian cancer.
Mansoor R. Mirza, Antonio González‐Martín, Whitney S. Graybill, David M. O’Malley, Lydia Gaba, Oi Wah Stephanie Yap, Eva M. Guerra, Peter G. Rose, Jean‐François Baurain, Sharad A. Ghamande, Hannelore Denys, Emily Prendergast, Carmela Pisano, Philippe Follana, Klaus Baumann, Paula M. Calvert, Jacob Korach, Yong Li, Izabela A. Malinowska, Divya Gupta, Bradley J. Monk   +20 more
wiley   +1 more source

Top advances of the year: Cervical cancer

Cancer, Volume 129, Issue 5, Page 657-663, 1 March 2023., 2023
Abstract Cervical cancer continues to affect women in the United States and throughout the world despite an effective vaccine against human papillomavirus and cancer screening programs. For the women who develop cervical cancer, surgery, radiation, and chemotherapy have been the mainstays of treatment for years.
Sarah E. Podwika, Linda R. Duska
wiley   +1 more source

Sinonasal inverted papilloma – malignant transformation and non‐sinonasal malignancies

The Laryngoscope, Volume 133, Issue 3, Page 506-511, March 2023., 2023
Objectives To assess malignant transformation rate, non‐sinonasal malignancies, and factors contributing to recurrence in patients treated for sinonasal inverted papilloma (SNIP). Study Design Retrospective study. Methods We retrospectively reviewed medical records of all patients treated for SNIP (n = 296) between the years 1984–2014 at Helsinki ...
Sanna Viitasalo, Taru Ilmarinen, Leena‐Maija Aaltonen, Jaana Hagström, Maija Hytönen, Sari Hammarén‐Malmi, Petra Pietarinen, Pia Järvenpää, Teemu Kinnari, Ahmed Geneid, Markus Lilja   +10 more
wiley   +1 more source

Benign descriptors and ADNEX in two‐step strategy to estimate risk of malignancy in ovarian tumors: retrospective validation in IOTA5 multicenter cohort

Ultrasound in Obstetrics &Gynecology, Volume 61, Issue 2, Page 231-242, February 2023., 2023
ABSTRACT Objective Previous work has suggested that the ultrasound‐based benign simple descriptors (BDs) can reliably exclude malignancy in a large proportion of women presenting with an adnexal mass. This study aimed to validate a modified version of the BDs and to validate a two‐step strategy to estimate the risk of malignancy, in which the modified ...
C. Landolfo, T. Bourne, W. Froyman, B. Van Calster, J. Ceusters, A. C. Testa, L. Wynants, P. Sladkevicius, C. Van Holsbeke, E. Domali, R. Fruscio, E. Epstein, D. Franchi, M. J. Kudla, V. Chiappa, J. L. Alcazar, F. P. G. Leone, F. Buonomo, M. E. Coccia, S. Guerriero, N. Deo, L. Jokubkiene, L. Savelli, D. Fischerova, A. Czekierdowski, J. Kaijser, A. Coosemans, G. Scambia, I. Vergote, D. Timmerman, L. Valentin   +30 more
wiley   +1 more source

Reproductive tract infection caused by Kocuria kristinae in an entire female sugar glider (Petaurus breviceps)

Veterinary Record Case Reports, Volume 10, Issue 4, December 2022., 2022
Abstract The presence of a cloaca in the reproductive tract of marsupials may predispose them to ascending infections. A 7‐year‐old, entire, female sugar glider presented with abdominal swelling. Whole‐body radiographs and abdominal ultrasound revealed a mass in the abdomen.
Tiziana Bassan, Alex Cobos, Claudia Mallol, Maria Lourdes Abarca, Jaume Martorell   +4 more
wiley   +1 more source

Platyfish bypass the constraint of the caudal fin ventral identity in teleosts

Developmental Dynamics, Volume 251, Issue 11, Page 1862-1879, November 2022., 2022
Abstract Background: The caudal fin of teleosts is characterized by dorsoventral symmetry. Despite this external morphology, the principal rays of this appendage connect to bones below the notochord, indicating the ventral (hypochordal) identity of this organ.
Lana Rees, Désirée König, Anna Jaźwińska   +2 more
wiley   +1 more source

Efeito da somatotropina bovina recombinante (rbST) na produção in vivo e na maturação in vitro de oócitos bovinos da raça Sindi [PDF]

Arquivo Brasileiro de Medicina Veterinária e Zootecnia
RESUMO A fim de avaliar o efeito de diferentes doses da rbST sobre a dinâmica folicular, a produção e a maturação in vitro de oócitos, 20 vacas Sindi, divididas em três grupos, receberam um dispositivo de progesterona intravaginal, estradiol e PGF2α ...
L.G.M. Ribeiro, B.D.M. Bastos, M.N.P. Silva, R.A. Oliveira, A.F.B.P. Pinto, I.R.A. Lima, L.H.A. Melo, R.K.C. Sousa, P.R. Gonçalves, H.C. Bonfa, M.F. Cordeiro, D.M. Nogueira, R.S. Barbosa, E.S. Lopes Júnior   +13 more
doaj   +2 more sources