Results 151 to 160 of about 385,031 (304)

Testicular SIRT1 Loss Reveals an Aging‐Like Proteomic Landscape and Precipitates Reproductive Deterioration

Andrology, EarlyView.
ABSTRACT Background Advanced paternal age is associated with reduced male fertility and testicular dysfunction. Among the molecular regulators involved in aging, SIRT1, a NAD+‐dependent deacetylase, plays a pivotal role in maintaining oxidative balance and cellular homeostasis.
María Iniesta‐Cuerda, Jiřina Havránková, Hedvika Řimnáčová, Jiří Moravec, František Liška, Martin Knytl, Milena Králíčková, Jan Nevoral   +7 more
wiley   +1 more source

Polydatin Relieves Airway Remodeling by Inhibiting P2X7R-NLRP3-Mediated Excessive Autophagy in Asthma. [PDF]

Immun Inflamm Dis
Li G, Li L, Wang Z, Piao Y, Song Y, Li L, Xu C, Li X, Yan G.   +8 more
europepmc   +1 more source

Alfabetización informacional (OVA)

, 2019
La gran cantidad de información que se genera a diario en el mundo y la variedad de soportes que la contienen ha traído como consecuencia que un usuario con una necesidad específica deba navegar durante más tiempo del que dispone; después queda con la incertidumbre de si esta información es la que verdaderamente necesita, si es confiable y valedera ...
openaire   +1 more source

Does synchronising follicular wave emergence improve outcomes in non‐superstimulated donor cattle undergoing ovum pick‐up (OPU) for in vitro embryo production?

Australian Veterinary Journal, EarlyView.
In vitro embryo production (IVEP) is now a widely commercialised assisted reproductive technology used in cattle reproduction. The use of follicle‐stimulating hormone (FSH) to superstimulate donor cattle prior to ovum pick‐up (OPU) is generally regarded as an effective strategy to improve oocyte quality, developmental competence and increase embryo ...
J Bird, RP Nevard
wiley   +1 more source

TLR9-activating cholesterol azetidine derivative-assisted therapeutic vaccines for cancer immunotherapy. [PDF]

Sci Adv
Chen J, Su M, Yu B, Yang M, Wang H, Yang X, Wang J.   +6 more
europepmc   +1 more source

Liminal Bioethics for Liminal Statuses: A New Method for Analysing Novel Biological Entities

Bioethics, EarlyView.
ABSTRACT Novel biological entities such as cell lines and organoids do not typically fit into established conceptual categories, such as ‘human’ or ‘nonhuman’, ‘gift’ or ‘property’. This makes developing robust ethical principles or policy solutions difficult.
Michael Wee, Ilina Singh
wiley   +1 more source

Are we hallucinating or can psychedelic drugs modulate the immune system to control inflammation?

British Journal of Pharmacology, EarlyView.
Psychedelic drugs that activate 5‐HT2A receptors have been long used for cultural, medicinal and recreational purposes. Interest in psychedelics for treating psychiatric disorders has resurged recently and is well documented; less well recognised are their anti‐inflammatory properties. Growing evidence now demonstrates that psychedelics modulate immune
Omar Qureshi, Jamie Cowley, Ashley Pegg, Alison J. Cooper, John Gordon, Catherine A. Brady, Antonio Belli, Sam Butterworth, Rachel Upthegrove, Nick Andrews, Nicholas M. Barnes   +10 more
wiley   +1 more source

A STING-activating biomimetic mineralized nanovaccine triggers robust anti-tumor immunity. [PDF]

Cancer Immunol Immunother
Tuo S, Wang Y, Tian M, Su L, Dong J, Lv K, He W, Feng Q, Chen S, Dong D, Li X, Zhong K, Zhang Y, Kong B, He L.   +14 more
europepmc   +1 more source

Advancements in Inorganic Chiral Nanomaterials for Anti‐Tumor Immunotherapy

Cancer Science, EarlyView.
Schematic illustration of how inorganic chiral nanomaterials enhance immune activation to promote tumor cell elimination through targeted delivery, immunogenic cell death, and immune microenvironment modulation. ABSTRACT While the past decade has witnessed unprecedented technological advancements, cancer remains a major health threat, with conventional
Siyu Chen, Qian Tang, Xiqian Chen, Yinghao Liang, Jin Qiu, Yongmei Liao, Changqiang Li, Hongru Yu, Fang Xie, Zongjunlin Liu   +9 more
wiley   +1 more source

Soluble gp130 inhibits Th17 polarization in neutrophilic asthma by blocking IL-6 <i>trans</i>-signaling in dendritic cells. [PDF]

Front Immunol
Zhu S, Yao Y, Lv T, Yao F, Xu J, Zhang A, Zhang F.   +6 more
europepmc   +1 more source