DISTANT HYBRIDS IN F4 (VITIS VINIFERA L. X MUSCADINIA ROTUNDIFOLIA MICHX.) AND OF CULTIVARS OF VITIS VINIFERA L. AND OF CONCERNING THE CONTENT OF SOME BIOCHEMICAL COMPOUNDS [PDF]
Scientific Papers Series : Management, Economic Engineering in Agriculture and Rural Development, 2015 The process of obtaining distant hybrids, as well as any crossing of cultivars of Vitis vinifera L. with representatives of species possessing the necessary qualities (resistance to diseases and pests, low temperature, etc.) may change the spectrum of ...
Eugeniu ALEXANDROV, Boris GAINA
doaj
Heterologous screening of hybridomas for the development of broad-specific monoclonal antibodies against deoxynivalenol and its analogues [PDF]
, 2014 Hapten heterology was introduced into the steps of hybridoma selection for the development of monoclonal antibodies (MAbs) against deoxynivalenol (DON).
Bracke, Marc +7 more
core +1 more source
O‐GlcNAcylated TAP1 Impairs Antigen Presentation and Promotes Immune Evasion in Bladder Cancer
Advanced Science, EarlyView.This article unveils a critical mechanism of immune evasion in bladder cancer, which the O‐GlcNAc modification of TAP1 disrupts antigen presentation. This modification triggers HLA‐A degradation, shielding tumor cells from CD8+ T cell attack. The findings highlight targeting this pathway as a promising therapeutic avenue to sensitize tumors to ...
Jinpeng Wu +10 more
wiley +1 more source
Clinical and Developmental Immunology, 2012 We examined whether maternal exposure to food antigens during lactation and maternal allergic status would affect the development of food allergy in offspring. OVA-sensitized or OVA-nonsensitized BALB/c female mice were exposed or unexposed to OVA during
Takeshi Yamamoto +4 more
doaj +1 more source
Immunological tolerance to muscle autoantigens involves peripheral deletion of autoreactive CD8+ T cells. [PDF]
PLoS ONE, 2012 Muscle potentially represents the most abundant source of autoantigens of the body and can be targeted by a variety of severe autoimmune diseases. Yet, the mechanisms of immunological tolerance toward muscle autoantigens remain mostly unknown.
Emilie Franck +7 more
doaj +1 more source
Yol uğraklarında:Altın ova! [PDF]
, 1935 Taha Toros Arşivi, Dosya Adı: Taha Torosİstanbul Kalkınma Ajansı (TR10/14/YEN/0033) İstanbul Development Agency (TR10/14/YEN ...
Toros, Taha
core
Restoring Conjunctival Tolerance by Topical Nuclear Factor–κB Inhibitors Reduces Preservative-Facilitated Allergic Conjunctivitis in Mice [PDF]
, 2014 Purpose.: To evaluate the role of nuclear factor–κB (NF-κB) activation in eye drop preservative toxicity and the effect of topical NF-κB inhibitors on preservative-facilitated allergic conjunctivitis.
Gabelloni, María Laura +6 more
core +1 more source
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
Advanced Science, EarlyView.T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
The Origins of New Zealand's Chinook Salmon, Oncorhynchus tshawytscha [PDF]
, 1994 Chinook salmon, Oncorhynchus tshawytscha, are well established as anadromous and landlocked runs in New Zealand. Ova introductions during the 1870's (probably from the McCloud River, California, U.S.A.), failed to generate anadromous stocks, but further ...
McDowall, Robert M.
core
Advanced Science, EarlyView.A multifaceted chemical strategy, integrating bacterial tropism, metal‐ion interference therapy, and immunotherapy, resulted in significant tumor regression in murine models. A pioneering paradigm for the design of biohybrid materials was established, highlighting how sophisticated chemical engineering of living systems can unlock new avenues for ...
Tingting Zhang +7 more
wiley +1 more source