Results 151 to 160 of about 102,497 (280)

Eliminating PD‐L1 on Dendritic Cell Extracellular Vesicles for Immunotherapy Potentiates Immune‐Mediated Tumour Rejection in Mice

Journal of Extracellular Vesicles, Volume 15, Issue 7, July 2026.
Extracellular vesicles (EVs) for immune therapy of cancer have both direct and indirect effects on immune cells. When taken up, the loaded antigen is presented by the host's dendritic cells (indirect). In this case, EV surface molecules like MHC‐peptide complexes on EVs are of minor importance. Here we show that removal of PD‐L1 from the surface of EVs
Loes Teeuwen, Loïc Steiner, Chantal Reinhardt, Annemarijn Offens, Jesse E. Kuipers, Daniel Martínez‐Martínez, Jules Mazouin, Benedict J. Chambers, Gözde Güçlüler Akpinar, Susanne Gabrielsson   +9 more
wiley   +1 more source

Sheath‐Liquid CE‐MS Interface: A Robust Infusion Platform for Native IMS‐MS Analysis of Protein Assemblies and Their Conformers

Journal of Mass Spectrometry, Volume 61, Issue 7, July 2026.
ABSTRACT Dynamic protein complexes are central to cellular function, but capturing their native architectures remains challenging. While native ion mobility spectrometry–mass spectrometry (IMS‐MS) can characterize these assemblies, its broader adoption is limited by the need for robust and automated sample introduction platforms.
Kanchan Pathak, Delaynie Brinkman, Fabio P. Gomes   +2 more
wiley   +1 more source

The potential of seedbank digital information in plant conservation

PLANTS, PEOPLE, PLANET, Volume 8, Issue 4, Page 1017-1028, July 2026.
Seedbanks are vital for biodiversity conservation, but their potential remains underutilised due to a limited understanding of the intraspecific genetic diversity they hold. By leveraging digitised data associated with seedbank collections, such as sampling locations, number of maternal plants and seed traits, we can attempt the estimation of genetic ...
Roberta Gargiulo, Sean Hoban, Anne M. Visscher, Pablo Gómez Barreiro, Roberta L. C. Dayrell, Kiran L. Dhanjal‐Adams, Alice R. Hudson, Charlotte E. Seal, Simon Kallow, Jan Sala, Lee Oliver, Naomi Carvey, Ted Chapman, Efisio Mattana, Clare Callow, Christopher Cockel, Michael F. Fay, Juan Viruel, Inna Birchenko, Stephanie Miles, Timothy Pearce, Paul Kersey, Elinor Breman, Kate A. Hardwick   +23 more
wiley   +1 more source

Thyme Essential Oil and Hyaluronic Acid as Natural Disinfectant Alternatives for Broiler Breeder Fertile Eggs: Effects on Eggshell Microbial Load, Embryonic Viability and Hatchability

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
Natural eggshell sanitation using thyme essential oil reduced microbial contamination and lipid peroxidation while improving embryo viability and hatchability in stored broiler breeder fertile eggs. These findings support thyme essential oil as a promising residue‐free alternative for hatchery egg sanitation.
Sinan Vicil, Fatma Tülin Özbaşer Bulut, Muazzez Gürgan Eser, Hakan Bulut   +3 more
wiley   +1 more source

Activation of tumor-specific CD8+ T cells prior to radiopharmaceutical therapy improves antitumor response. [PDF]

J Immunother Cancer
Shim D, Mouton C, Moseman JE, Comas Rojas H, Jeon D, Idrissou MB, Hernandez R, Weichert JP, McNeel DG.   +8 more
europepmc   +1 more source

Antioxidants in Plant‐Based Food Matrices: From Structure–Activity and Degradation Kinetics to Formulation Design

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 4, July 2026.
ABSTRACT Plant‐based antioxidants are widely incorporated into foods to retard oxidative deterioration and to deliver health‐related benefits. Yet, their in‐product and in vivo performance frequently diverges from predictions based on solution‐phase chemical assays, because matrix interactions, processing history, and host metabolism reshape both ...
Márcio Vargas‐Ramella, Carmen Silvia Favaro‐Trindade, Bárbara Miranda‐Vilela, Mariana Estefanuto‐Costa, Marina Franco‐Brito, Bibiana Alves dos Santos, Paulo Cezar Bastianello Campagnol   +6 more
wiley   +1 more source

Research note: Application and validation of RP-HPLC for quantifying ovomucoid, lysozyme, ovotransferrin, and ovalbumin in commercial pasteurized egg white. [PDF]

Poult Sci
Sousa I, Visentin E, Sabbadin S, Pozza M, Birolo M, De Marchi M, Niero G.   +6 more
europepmc   +1 more source

Are we hallucinating or can psychedelic drugs modulate the immune system to control inflammation?

British Journal of Pharmacology, Volume 183, Issue 14, Page 4006-4021, July 2026.
Psychedelic drugs that activate 5‐HT2A receptors have been long used for cultural, medicinal and recreational purposes. Interest in psychedelics for treating psychiatric disorders has resurged recently and is well documented; less well recognised are their anti‐inflammatory properties. Growing evidence now demonstrates that psychedelics modulate immune
Omar Qureshi, Jamie Cowley, Ashley Pegg, Alison J. Cooper, John Gordon, Catherine A. Brady, Antonio Belli, Sam Butterworth, Rachel Upthegrove, Nick Andrews, Nicholas M. Barnes   +10 more
wiley   +1 more source

Degradomics for large‐scale mechanistic insights on proteases and proteolysis in human health

The FEBS Journal, Volume 293, Issue 13, Page 3881-3898, July 2026.
Proteolysis has an important role in human disease but remains relatively unexplored. Degradomics, the uncovering of proteolysis in tissues, cells, and proteins, uses mass spectrometry‐based terminomics to identify protein termini occurring therein (forward degradomics) and to define the actions of proteases (reverse degradomics).
Daniel R. Martin, Sumit Bhutada, Suneel S. Apte   +2 more
wiley   +1 more source

Imprecise Cas12a/ssODN‐Mediated Editing of eIF4E1 Confers Dominant‐Negative Resistance to Potato Virus Y in Solanum tuberosum

Molecular Plant Pathology, Volume 27, Issue 7, July 2026.
Efforts to mimic the pepper PVY‐resistant pvr21 allele in potato using Cas12a‐mediated single‐stranded oligodeoxynucleotide (ssODN) editing of eIF4E1, while highlighting key technical limitations, shed light on a dominant‐negative PVY resistance mechanism.
Alessandra Lucioli, Raffaela Tavazza, Attila Molnar, Vincenza Ilardi, Adéla Přibylová, Mario Tavazza   +5 more
wiley   +1 more source