Results 141 to 150 of about 755,388 (347)

Replication catastrophe is responsible for intrinsic PAR glycohydrolase inhibitor-sensitivity in patient-derived ovarian cancer models [PDF]

open access: gold, 2021
Camilla Coulson‐Gilmer   +12 more
openalex   +1 more source

Functional Integration of Different‐Sex Gonad Transplants Into the Adult Mouse Hypothalamic Pituitary Gonadal Axis

open access: yesAdvanced Biology, EarlyView.
This study introduces and investigates different‐sex gonad transplants in a mouse model of gender‐affirming hormone therapy. Ovaries and testes implanted into gonadectomized adults exhibit gametogenesis and steroidogenesis independent of the sex of the host.
Daniel R. Pfau   +8 more
wiley   +1 more source

Ran promotes membrane targeting and stabilization of RhoA to orchestrate ovarian cancer cell invasion [PDF]

open access: gold, 2019
Kossay Zaoui   +5 more
openalex   +1 more source

The origin of ovarian cancer

open access: yesBJOG: An International Journal of Obstetrics & Gynaecology, 2011
Please cite this paper as: Ahmed A, Becker C, Bast R Jr. The origin of ovarian cancer. BJOG 2012;119:134–136.
Ahmed, A, Becker, C, Bast, R
openaire   +2 more sources

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

open access: yesAdvanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth   +2 more
wiley   +1 more source

Extracellular‐Matrix‐Based Materials from Decellularized Tissue: Opportunities, Challenges, and Future Directions in Regenerative Medicine

open access: yesAdvanced Healthcare Materials, EarlyView.
Extracellular matrix‐based materials derived from decellularized tissue (dECM) harness the tissue's native bioactivity to guide repair and regeneration across diverse clinical applications. This perspective highlights clinical uses of dECM biomaterials and advances in fabrication methods such as electrospinning and 3D printing.
Madeline Laude   +4 more
wiley   +1 more source

Engineering adoptive T cell therapy to co-opt Fas ligand-mediated death signaling in ovarian cancer enhances therapeutic efficacy [PDF]

open access: gold, 2022
Kristin G. Anderson   +6 more
openalex   +1 more source

Multiplexed Luminal Tissue Constructs with Reconfigurable Barriers for Dynamic Modeling of Multi‐Tissue Interactions

open access: yesAdvanced Materials Technologies, EarlyView.
This study describes the fabrication of arrays of luminal tissue constructs for 3D luminal tissue modeling. An oil or media‐filled reservoir between constructs serves as a liquid barrier or bridge to regulate communication between lumens within the array for modeling multi‐tissue interactions in vitro. Abstract Cell‐lined luminal structures are crucial
Mouhita Humayun   +9 more
wiley   +1 more source

Fertility-Sparing Surgery in Early Epithelial Ovarian Cancer: A Viable Option?

open access: yesObstetrics and Gynecology International, 2012
Epithelial ovarian cancer (EOC) continues to represent one of the most lethal conditions in women in the western countries. With the shifting of childbearing towards higher age, EOC increasingly affects women with active childbearing wish, resulting in ...
Christina Fotopoulou   +2 more
doaj   +1 more source

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