Results 161 to 170 of about 352,140 (294)

Macrophage Extracellular Traps in Immunity and Cancer

Advanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li, Eugenie Nepovimova, Adam Grundel, Lukas Peter, Qinghua Wu, Kamil Kuca   +5 more
wiley   +1 more source

Mechanisms of inflammation in premature ovarian insufficiency and advances in therapeutic studies. [PDF]

Front Immunol
Chen Y, Xu Y, Lu Y, Li W, Tao F, Zhao Y.
europepmc   +1 more source

Systems biology strategy for drug potentiating through drug repurposing:bisphosphonates beyond osteoporosis treatment [PDF]

, 2018
Goltsov, Alexey, Kowalczyk, Zuzanna, Papineni, Rao V. L.   +2 more
core   +2 more sources

IGFBP5 Restores Endometrial Receptivity and Rescues Implantation Failure in Polycystic Ovary Syndrome

Advanced Science, EarlyView.
Impaired endometrial receptivity contributes to the poor pregnancy outcomes in women with PCOS. The authors found that decreased endometrial IL‐22 levels and disrupted STAT3‐IGFBP5 signaling pathway contributed to impaired endometrial receptivity. Supplementation with IL‐22 or IGFBP5 exerts a protective effect on implantation failure in PCOS‐like mice,
Baoying Liao, Chuyu Yun, Hongying Shan, Yuqian Wang, Xiunan Chen, Weisi Lian, Tianliu Peng, Min Zhao, Xunsi Qin, Kailun Hu, Ping Zhou, Yue Wang, Yanli Pang, Rong Li   +13 more
wiley   +1 more source

Coexistence of Ovarian Mature Cystic Teratomas and Endometriosis: An Update. [PDF]

Int J Womens Health
Lin C, Chae HS.
europepmc   +1 more source

Development of ovarian diseases in dairy cows with a history of fatty liver, and their prognosis. [PDF]

J Vet Med Sci, 2016
Tanemura K, Ohtaki T, Ono M, Tsumagari S.   +3 more
europepmc   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Association of Smoking and Alcohol Consumption with Female Reproductive Diseases: A Mendelian Randomization Study on the Mediating Role of Circulating Metabolites. [PDF]

Int J Womens Health
Li C, Jiang Z, Bai J, Li M, Li M, Wu X, Zhang Y, Li B, Xie Q, Li F, Ran M, Dang H.   +11 more
europepmc   +1 more source

Leveraging Macrophage Metabolic Reprogramming for Enhanced Anti‐Tumor Immunity

Advanced Science, EarlyView.
Tumor‐associated macrophages (TAMs) are key regulators of the tumor microenvironment (TME), with their metabolic states playing a critical role in tumor progression or regression. This review summarizes current understanding of TAM metabolic plasticity alongside cutting‐edge bioengineering innovations, outlining a roadmap for transforming the ...
Zhiyun Liu, Lingyao Zeng, Xulin Gan, Yilin Zhou, Han Shen, Dan Wu, Xin Shou, Minmin Jiang, Liyun Shi   +8 more
wiley   +1 more source

Bacterial Infections Role in Gynecological Cancers Development: Narrative Review. [PDF]

Cancer Rep (Hoboken)
Azargun R, Azargoon M, Asefy Z, Yekani M, Tarhriz V, Yeganeh F, Memar MY, Eyvazi S.   +7 more
europepmc   +1 more source