Results 191 to 200 of about 2,535,326 (289)

Integrating Next-Generation Reproductive Organoids with Genomics, Multi-Omics and Bioengineering to Understand Human Infertility. [PDF]

Genes (Basel)
Barreau P, Djari C, De Vos J, Cassuto NG, Assou S.   +4 more
europepmc   +1 more source

Targeted Lysosomal Degradation of Extracellular and Membrane Proteins: From Receptor Hijacking to Programmable Endolysosomal Routing

Advanced Science, EarlyView.
Targeted chimeric degraders engage extracellular or membrane proteins and endocytosable cell‐surface receptors, forming ternary complexes that induce receptor‐mediated internalization. Following endocytosis, post‐endocytic sorting—not internalization alone—determines target fate.
Ke Liu, Xiyan Wang, Xiaozhen Liu, Chaoqi He, Da Qian, Xuli Meng, Liquan Zhu   +6 more
wiley   +1 more source

Research progress on protein lactylation in female reproductive disease: molecular mechanisms, functions, and therapeutic implications. [PDF]

Front Pharmacol
Shen X, Chen Y, Deng H, Zhang N, Xu L.
europepmc   +1 more source

SOX30 Facilitates Triple‐Negative Breast Cancer Metastasis via TNFR2–NF‐κB Signaling and Tumor Microenvironment Remodeling

Advanced Science, EarlyView.
SOX30 drives triple‐negative breast cancer (TNBC) metastasis through a dual mechanism: direct activation of the TNFR2/NF‐κB signaling cascade and subsequent CCL20‐mediated recruitment of tumor‐associated macrophages (TAMs) into the tumor microenvironment.
Pingping Gao, Na Sun, Ning Yang, Tingting Zhao, Rui Fu, Zhenyu Wu, Yuqin Zhou, Xuanni Tan, Yi Zhang, Fei Han, Xiaowei Qi   +10 more
wiley   +1 more source

NR4A1-Driven Granulosa Cell Ferroptosis Contributes to Obesity-Related Ovarian Dysfunction and Metformin-Mediated Ovarian Protection. [PDF]

FASEB J
Wang H, Wang C, Guo S, Yang G, Fang J, Hu J, Jiang R, Zhai J, Jin H, Song W, Shi S, Huang X, Qi L, Wu Z, Liu Y, Song N, Zhang X, Yao G.   +17 more
europepmc   +1 more source

Development of ovarian diseases in dairy cows with a history of fatty liver, and their prognosis. [PDF]

J Vet Med Sci, 2016
Tanemura K, Ohtaki T, Ono M, Tsumagari S.   +3 more
europepmc   +1 more source

Biomimetic Scaffold‐Based 3D Models for Decoding Cancer Biology and Advancing Therapy

Advanced Science, EarlyView.
A timeline of the research history of 3D biomimetic scaffold materials and platforms. With advances in biomimetic materials and 3D scaffold technologies, their functional scope has expanded from mimicking basic physical and biochemical properties to increasingly replicating complex pathophysiological processes.
Haitao Zhao, Yuechen Han, Jie Li, Peng Luo, Lin Qi, Zhiwei Xia, Xiaosong Li, Quan Cheng, Chenshen Huang, Wantao Wu, Hao Zhang   +10 more
wiley   +1 more source

Quantitative Parameters of Contrast-Enhanced Ultrasonography (CEUS) Monitoring Ovarian Hemodynamics in Rats. [PDF]

Vet Radiol Ultrasound
Luo Z, Yang T, Luo X, Wang Y, Wang L, Ren R, Zhou X, Zhang X.   +7 more
europepmc   +1 more source

MAPA: A Semantic Network Framework for Functional Module Discovery and Interpretation in Multi‐Omics Data

Advanced Science, EarlyView.
MAPA transforms complex multi‐omics data into biologically coherent functional modules by integrating pathway information with molecular interaction networks. Retrieval‐augmented large language models then generate structured, literature‐informed interpretations.
Yifei Ge, Feifan Zhang, Yijiang Liu, Chao Jiang, Peng Gao, Nguan Soon Tan, Sai Zhang, Yuchen Shen, Qianyi Zhou, Xin Zhou, Xiao Wang, Fangqing Zhao, Chuchu Wang, Xiaotao Shen   +13 more
wiley   +1 more source

Pseudo-Pseudo Meigs' Syndrome-Like Presentation Associated with Primary Sjögren's Syndrome: A Case Report. [PDF]

J Inflamm Res
Xun J, Liu X, Chang B, Wang X, Peng C, Yang P, Liu X.   +6 more
europepmc   +1 more source