Results 231 to 240 of about 349,716 (299)

Causal relationship between diet and common female diseases: a comprehensive Mendelian randomization study. [PDF]

BMC Womens Health
Fu M, Deng F, Chen J, Wen M, Zhu X, Fu L, Guan J, Qiu J, Gao Q, Ding H.   +9 more
europepmc   +1 more source

Endometrial Epithelial Lactate Deficiency Drives CD8+ T‐Cells Dysregulation in Unexplained Recurrent Implantation Failure

Advanced Science, EarlyView.
Unexplained recurrent implantation failure (RIF) represents a significant clinical challenge. Our results demonstrate that reduced lactate production in the RIF endometrium impairs the suppression of cytotoxic CD8+ T‑cells, allowing their proliferation and thereby disrupting the local immune balance essential for successful embryo implantation.
Yuanlin He, Kang Ke, Qingxia Meng, Yichun Guan, Jichun Tan, Hong Lv, Boxian Huang, Chan Tian, Qinyan Zou, Mingxing An, Yao Gao, Jingjing Chen, Xiaoyu Wei, Xi Wang, Hongxia Ma, Yuan Lin, Feiyang Diao, Yayun Gu, Zhibin Hu   +18 more
wiley   +1 more source

Cell-intrinsic and tumor microenvironmental determinants of platinum resistance in epithelial ovarian cancer. [PDF]

Discov Oncol
Chen W, Shi W, Chan HL, Wang Y, Di W.
europepmc   +1 more source

Tumor‐Induced Splenic Remodeling: Mechanisms of Systemic Immunosuppression and Emerging Therapeutic Opportunities

Advanced Science, EarlyView.
ABSTRACT Despite the transformative impact of cancer immunotherapies such as immune checkpoint blockade, durable clinical responses remain limited. Increasing evidence indicates that antitumor immunity is governed not only by the tumor microenvironment, but also by systemic immune regulation mediated by peripheral immune organs. Among these, the spleen
Yuehua Liu, Xiaoqian Nie, Xiaofei Gao
wiley   +1 more source

Repurposing trifluoperazine as a potential therapeutic agent for ovarian cancer: mechanistic insight via SRC/PI3K/AKT signaling pathway inhibition. [PDF]

J Ovarian Res
He Q, Mei J, Cai D, Yan Q, Zhang Y, Deng Y, Li W, Xiong J, Wan J, He Y.   +9 more
europepmc   +1 more source

Novel gene variants in a rare case of SRY-negative 46, XX male syndrome with bone marrow failure by whole exome sequencing. [PDF]

Blood Sci
Zhang A, Liu L, Ruan M, Zhang L, Zou Y, Chen Y, Zhang Y, Yang W, Zhu X, Chang L.   +9 more
europepmc   +1 more source

Primary Peritoneal Low-Grade Serous Carcinoma in a 16-Year-Old Female: A Case Report. [PDF]

J Clin Med
An Y, Fan Y, Xia Y.
europepmc   +1 more source

FSHR-targeting tetrahedral DNA frameworks ameliorate ovarian aging through oxidative stress elimination. [PDF]

J Nanobiotechnology
Dai Y, Guo Y, Chen D, Li P, Xue L, Feng Y, Tang W, Wu C, Wei S, Dai J, Jiang D, Wang S, Wu M.   +12 more
europepmc   +1 more source

Clinical practice guideline for female fertility preservation. [PDF]

Front Med (Lausanne)
Sun N, Ding H, Cai L, Chian RC, Deng X, Guan Y, Jin L, La X, Lin G, Ling X, Lou Z, Lu W, Lv Q, Ma F, Pei X, Quan S, Shen J, Tao M, Wang L, Wang X, Xiong G, Xu J, Xu P, Xu W, Yao Y, Yuan X, Zhang F, Zhang Q, Zhang Q, Zhang X, Zhou P, Li W.   +31 more
europepmc   +1 more source