Results 171 to 180 of about 58,363 (266)

Ovarian Follicle Evaluation: Antral Follicle Count and Follicle Monitoring During Controlled Ovarian Stimulation [PDF]

, 2016
openaire   +1 more source

Loss‐of‐Function Variants in CCDC189 Cause Human Oligoasthenoteratozoospermia by Disrupting Sperm Flagellar and Acrosomal Architecture

Andrology, EarlyView.
ABSTRACT Background Oligoasthenoteratozoospermia (OAT), characterized by reduced sperm count, impaired motility, and abnormal morphology, is a major cause of male infertility with substantial genetic heterogeneity. However, the underlying genetic etiology remains unresolved in a large proportion of affected individuals.
Jianteng Zhou, Ghulam Mustafa, Tingting Lin, Jingwei Ye, Huan Zhang, Hanwei Jiang, Kexin Yang, Guoning Huang, Qinghua Shi   +8 more
wiley   +1 more source

17β-estradiol and estrogen receptor alpha protect mouse ovarian follicle development by repressing atresia. [PDF]

iScience
Ueno E, Watanabe M, Kondo Y, Nakagata N, Takeo T, Nakao S, Ogiwara K.   +6 more
europepmc   +1 more source

Ultrasonographic features of the platypus abdomen via a limited left pre‐epipubic acoustic window from a series of 54 individuals

Australian Veterinary Journal, EarlyView.
Introduction There are notable differences between the platypus and common species of domestic mammal in the location and structure of some abdominal organs. The aim of this study was to detail the size, position and relative locations of organs in the left side of the platypus abdomen, to assist evidence‐based decision‐making in a clinical setting ...
JW Macgregor, RA Lonsdale, C Holyoake, JH Connolly, ID Robertson, R Donaldson, K Warren   +6 more
wiley   +1 more source

Coordinating Fertility Preservation in Children and Young Adults at Risk of Treatment‐Induced Infertility: A Commentary

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
Ursula Blyth, Pedro Melo, Rod T. Mitchell, Suzannah A. Williams, Ephia Yasmin, Phillipa Sangster, Kokila Lakhoo, Sheila Lane, Richard A. Anderson, Christian M. Becker   +9 more
wiley   +1 more source

Gold‐standard evidence and best practice guidance for menstrual cycle‐informed clinical care: An overview for clinicians

British Journal of Clinical Psychology, EarlyView.
Abstract Objectives To synthesize current evidence and provide clinically actionable recommendations for integrating menstrual cycle‐related processes—particularly hormone sensitivity, Premenstrual Dysphoric Disorder (PMDD) and Premenstrual Exacerbation (PME)—into psychological assessment, formulation and treatment.
Ellen R. Lambert, Louise N. Nolan, Katja M. Schmalenberger   +2 more
wiley   +1 more source

Transcriptome Sequencing Analysis of Genes Associated with Different Developmental Periods of the Ovarian Follicle in the Duolang Sheep. [PDF]

Genes (Basel)
Wang C, Yan H, Hao W, Li F, Liu T, Wang H.   +5 more
europepmc   +1 more source

Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt

British Journal of Pharmacology, EarlyView.
Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown, Alan Armstrong, David J. Mann   +2 more
wiley   +1 more source

Granulosa cells provide transcriptomic information on ovarian follicle dynamics in southern white rhinoceros. [PDF]

Sci Rep
Klohonatz K, Durrant B, Sirard MA, Ruggeri E.   +3 more
europepmc   +1 more source

Targeting KRAS for cancer therapy

British Journal of Pharmacology, EarlyView.
In recent years, therapeutics targeted against KRAS proto‐oncogene GTPase (KRAS)‐mutant cancers have seen significant progress. Herein we outline the biology and epidemiology of KRAS alterations at the lineage and allele levels, reviewing the clinical evidence for KRASG12C inhibition from the discovery of the recessive switch pocket to sotorasib ...
Jianlong Jia, Ruonan Liu, Tonia A. Adamide, Isis E. Fernandez, Georgios T. Stathopoulos   +4 more
wiley   +1 more source