Results 21 to 30 of about 55,590 (315)

Do BRCA1 and BRCA2 gene mutation carriers have a reduced ovarian reserve? Protocol for a prospective observational study

BMJ Open, 2019
Introduction BRCA1/2 gene mutations increase risk of breast and/or ovarian cancer and may have implications for reproductive health. Indirect biomarkers of the ovarian primordial follicle pool (anti-Müllerian hormone (AMH)) and one small study in female ...
Amy Louise Winship, Chris Willson, Karl R Hansen, Karla J Hutt, Martha Hickey   +4 more
doaj   +1 more source

Effects of hypoxia-preconditioned HucMSCs on neovascularization and follicle survival in frozen/thawed human ovarian cortex transplanted to immunodeficient mice

Stem Cell Research & Therapy, 2022
Background The massive loss of follicles in the early stage of ovarian tissue transplantation is considered a significant restriction to the efficacy of ovarian tissue cryopreservation (OTC) and transplantation (OT).
Jiaojiao Cheng, Xiangyan Ruan, Yanglu Li, Juan Du, Fengyu Jin, Muqing Gu, Qi Zhou, Xin Xu, Yu Yang, Husheng Wang, Alfred Otto Mueck   +10 more
doaj   +1 more source

Human Ovarian Follicles Xenografted in Immunoisolating Capsules Survive Long Term Implantation in Mice

Frontiers in Endocrinology, 2022
Female pediatric cancer survivors often develop Premature Ovarian Insufficiency (POI) owing to gonadotoxic effects of anticancer treatments. Here we investigate the use of a cell-based therapy consisting of human ovarian cortex encapsulated in a poly ...
Margaret A. Brunette, Hadrian M. Kinnear, Hadrian M. Kinnear, Prianka H. Hashim, Colleen L. Flanagan, James R. Day, Marilia Cascalho, Marilia Cascalho, Vasantha Padmanabhan, Vasantha Padmanabhan, Ariella Shikanov, Ariella Shikanov, Ariella Shikanov   +12 more
doaj   +1 more source

Non-coding RNAs in the Ovarian Follicle [PDF]

Frontiers in Genetics, 2017
The mammalian ovarian follicle is the complex reproductive unit comprising germ cell, somatic cells (Cumulus and Granulosa cells), and follicular fluid (FF): paracrine communication among the different cell types through FF ensures the development of a mature oocyte ready for fertilization.
Battaglia, Rosalia, Vento, Maria E., Borzì, Placido, Ragusa, Marco, Barbagallo, Davide, Arena, Desirée, Purrello, Michele, di Pietro, Cinzia   +7 more
openaire   +4 more sources

Female reproductive aging is master-planned at the level of ovary.

PLoS ONE, 2014
The ovary receives a finite pool of follicles during fetal life. Atresia remains the major form of follicular expenditure at all stages since development of ovary.
Sayani Banerjee, Sutapa Banerjee, Ghungroo Saraswat, Soma Aditya Bandyopadhyay, Syed N Kabir   +4 more
doaj   +1 more source

Is there a relationship between ovarian reserve and blood groups in infertile patients?

Gynecology Obstetrics & Reproductive Medicine, 2019
Objective: Evaluation of ovarian reserve in infertile patients had become an important concept in assisted reproductive techniques (ART) success work-up. Recent studies reported an association between blood type and ovarian reserve. Therefore, the aim of
Ozgur Kan, Umit Gorkem, Aysegul Alkilic, Deniz Taskiran, Ozgur Kocak, Engin Yildirim, Cihan Togrul   +6 more
doaj   +1 more source

Prediction of the Spontaneous Estrus Expression Period Based on Large (≥10 mm) Follicle Numbers in Lactating Holstein Dairy Cows

Veterinary Sciences, 2023
The objectives of this study were (1) to investigate the distribution of large (≥10 mm) follicle numbers during the estrous cycle and (2) to compare the timing of the estrus expression period after the ovarian examination between cows with one large ...
Ryotaro Miura, Takuma Inoue, Yuka Kunugi, Miya Yasukawa, Saku Koyama, Rena Sato, Tomochika Matsumura, Tsuyoshi Tajima, Itaru Yoshimura, Tadaharu Ajito   +9 more
doaj   +1 more source

Dynamic genome-scale cell-specific metabolic models reveal novel inter-cellular and intra-cellular metabolic communications during ovarian follicle development

BMC Bioinformatics, 2019
Background The maturation of the female germ cell, the oocyte, requires the synthesis and storing of all the necessary metabolites to support multiple divisions after fertilization.
Beatriz Peñalver Bernabé, Ines Thiele, Eugene Galdones, Anaar Siletz, Sriram Chandrasekaran, Teresa K. Woodruff, Linda J. Broadbelt, Lonnie D. Shea   +7 more
doaj   +1 more source

Female reproductive decline is determined by remaining ovarian reserve and age. [PDF]

PLoS ONE, 2014
The early decline and loss of female fertility in humans and other species represents an evolutionary paradox. Despite being born with a vast stock of oocytes, females encounter an exhaustion of ovarian reserve and sterility half way through their ...
Pawel Wilkosz, Gareth D Greggains, Tom G Tanbo, Peter Fedorcsak   +3 more
doaj   +1 more source

Calcification of the Ovarian Follicle in Rats.

Experimental Biology and Medicine, 1964
SummaryThe induction of calcification in rat ovarian follicles by administration of parathyroid extract is reported. Calcium deposition is limited to the membrane granulosa and thecae interna of follicles in the early stages of antrum formation. It is suggested that the “calcifiability” of these tissues may be due in part to an action of endogenous ...
Howard S. Grob, Herbert S. Kitpperman, Albert S. Gordon   +2 more
openaire   +3 more sources