Results 41 to 50 of about 307,578 (312)

Animal models of ovarian cancer. [PDF]

open access: yes, 2003
Ovarian cancer is the most lethal of all of the gynecological cancers and can arise from any cell type of the ovary, including germ cells, granulosa or stromal cells.
Jean-François Ethier   +11 more
core   +1 more source

Non-coding RNAs in the Ovarian Follicle [PDF]

open access: yesFrontiers in Genetics, 2017
The mammalian ovarian follicle is the complex reproductive unit comprising germ cell, somatic cells (Cumulus and Granulosa cells), and follicular fluid (FF): paracrine communication among the different cell types through FF ensures the development of a mature oocyte ready for fertilization.
Battaglia, Rosalia   +7 more
openaire   +3 more sources

Dynamic genome-scale cell-specific metabolic models reveal novel inter-cellular and intra-cellular metabolic communications during ovarian follicle development

open access: yesBMC Bioinformatics, 2019
Background The maturation of the female germ cell, the oocyte, requires the synthesis and storing of all the necessary metabolites to support multiple divisions after fertilization.
Beatriz Peñalver Bernabé   +7 more
doaj   +1 more source

Changes in expression of TNF alpha and its receptors mRNAs in oocytes and granulosa cells in mice with experimental immune ovarian failure [PDF]

open access: yes, 2014
Purpose: To investigate the expression of TNF- α and its receptors (types I and II) at mRNA level in oocytes and granulose cells as well as to study effect of TNF-α on follicular cell death in mice with experimental immune ovarian failure induced by ...
Grushka, Nataliya   +4 more
core   +1 more source

Prediction of the Spontaneous Estrus Expression Period Based on Large (≥10 mm) Follicle Numbers in Lactating Holstein Dairy Cows

open access: yesVeterinary Sciences, 2023
The objectives of this study were (1) to investigate the distribution of large (≥10 mm) follicle numbers during the estrous cycle and (2) to compare the timing of the estrus expression period after the ovarian examination between cows with one large ...
Ryotaro Miura   +9 more
doaj   +1 more source

The relation between variation in size of the primordial follicle pool and age at natural menopause [PDF]

open access: yes, 2015
Context: Tumors producing insulin-like growth factor 2 (IGF-2oma) are a major cause of spontaneous hypoglycemia. The treatment mainstay is surgical resection.
van der Schouw, Yvonne   +29 more
core   +2 more sources

Ovarian antral follicle number and the amount of gonadotropin used in ovarian stimulation in polycystic ovarian patients.

open access: yesمجلة كلية الطب, 2011
Background: Polycystic ovary syndrome is the most common cause of anovulation, and the number of antral follicles is of great importance in determining ovarian reserve, so identification of patients with diminished ovarian reserve help in choosing ...
Hanan L. Sudek
doaj   +1 more source

Fertility preservation for girls and young women with cancer: population-based validation of criteria for ovarian tissue cryopreservation [PDF]

open access: yes, 2014
Background: Ovarian tissue cryopreservation with later reimplantation has been shown to preserve fertility in adult women, but this approach remains unproven and experimental in children and adolescents.
Edgar, Angela E   +4 more
core   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Female reproductive decline is determined by remaining ovarian reserve and age. [PDF]

open access: yesPLoS ONE, 2014
The early decline and loss of female fertility in humans and other species represents an evolutionary paradox. Despite being born with a vast stock of oocytes, females encounter an exhaustion of ovarian reserve and sterility half way through their ...
Pawel Wilkosz   +3 more
doaj   +1 more source

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