Results 31 to 40 of about 69,721 (316)

Evaluation of an alternative heterotopic transplantation model for ovarian tissue to test pharmaceuticals improvements for fertility restoration

Reproductive Biology and Endocrinology, 2022
Background Ovarian tissue cryopreservation and transplantation (OTCTP) is currently the main option available to preserve fertility in prepubertal patients undergoing aggressive cancer therapy treatments.
Carmen Terren, Jules Bindels, Michelle Nisolle, Agnès Noël, Carine Munaut   +4 more
doaj   +1 more source

Comparative Tensile Properties and Collagen Patterns in Domestic Cat (Felis catus) and Dog (Canis lupus familiaris) Ovarian Cortical Tissues

Bioengineering, 2023
The importance of the ovarian extracellular environment and tissue rigidity on follicle survival and development has gained attention in recent years.
Jennifer B. Nagashima, Shoshana Zenilman, April Raab, Helim Aranda-Espinoza, Nucharin Songsasen   +4 more
doaj   +1 more source

Effects of hypoxia-preconditioned HucMSCs on neovascularization and follicle survival in frozen/thawed human ovarian cortex transplanted to immunodeficient mice

Stem Cell Research & Therapy, 2022
Background The massive loss of follicles in the early stage of ovarian tissue transplantation is considered a significant restriction to the efficacy of ovarian tissue cryopreservation (OTC) and transplantation (OT).
Jiaojiao Cheng, Xiangyan Ruan, Yanglu Li, Juan Du, Fengyu Jin, Muqing Gu, Qi Zhou, Xin Xu, Yu Yang, Husheng Wang, Alfred Otto Mueck   +10 more
doaj   +1 more source

Effect of androgen treatment during foetal and/or neonatal life on ovarian function in prepubertal and adult rats [PDF]

, 2012
We investigated the effects of different windows of testosterone propionate (TP) treatment during foetal and neonatal life in female rats to determine whether and when excess androgen exposure would cause disruption of adult reproductive function ...
Alan S McNeilly, Amanda J Drake, Michelle Welsh, Broyde, Marie, Tyndall, Victoria, Welsh, M., McNeilly, Alan S, Drake, Amanda J, Victoria Tyndall, Richard Sharpe, Marie Broyde, Broyde, M., Welsh, Michelle, Sharpe, Richard, McNeilly, A.S., Drake, A.J., Sharpe, R., Tyndall, V.   +17 more
core   +1 more source

Maturation of ovarian follicles in the prepubertalgilt [PDF]

Bioscientifica Proceedings, 2020
The processes of follicle development and puberty are closely related, and both are associated with maturation of the hypothalamic-pituitary-ovarian axis. Prenatal development of the ovary is independent of gonadotrophic stimulation. Beyond 60 days of age (postnatally), tertiary follicles develop and gonadotrophins begin to influence ovarian follicular
R K, Christenson, J J, Ford, D A, Redmer
openaire   +2 more sources

Senataxin: A New Guardian of the Female Germline Important for Delaying Ovarian Aging

Frontiers in Genetics, 2021
Early decline in ovarian function known as premature ovarian aging (POA) occurs in around 10% of women and is characterized by a markedly reduced ovarian reserve.
Hayden A. Homer
doaj   +1 more source

Ovarian volume correlates strongly with the number of non-growing follicles in the human ovary [PDF]

, 2012
A reliable indirect measure of ovarian reserve for the individual woman remains a challenge for reproductive specialists. Using descriptive statistics from a large-scale study of ovarian volumes, we have developed a normative model for healthy females ...
Kelsey, Tom, Wallace, W Hamish B, Thomas W. Kelsey, Wallace, W. Hamish B., Kelsey, Thomas W., W. Hamish B. Wallace   +5 more
core   +1 more source

Do BRCA1 and BRCA2 gene mutation carriers have a reduced ovarian reserve? Protocol for a prospective observational study

BMJ Open, 2019
Introduction BRCA1/2 gene mutations increase risk of breast and/or ovarian cancer and may have implications for reproductive health. Indirect biomarkers of the ovarian primordial follicle pool (anti-Müllerian hormone (AMH)) and one small study in female ...
Amy Louise Winship, Chris Willson, Karl R Hansen, Karla J Hutt, Martha Hickey   +4 more
doaj   +1 more source

Human Ovarian Follicles Xenografted in Immunoisolating Capsules Survive Long Term Implantation in Mice

Frontiers in Endocrinology, 2022
Female pediatric cancer survivors often develop Premature Ovarian Insufficiency (POI) owing to gonadotoxic effects of anticancer treatments. Here we investigate the use of a cell-based therapy consisting of human ovarian cortex encapsulated in a poly ...
Margaret A. Brunette, Hadrian M. Kinnear, Hadrian M. Kinnear, Prianka H. Hashim, Colleen L. Flanagan, James R. Day, Marilia Cascalho, Marilia Cascalho, Vasantha Padmanabhan, Vasantha Padmanabhan, Ariella Shikanov, Ariella Shikanov, Ariella Shikanov   +12 more
doaj   +1 more source

The effects of uterine artery embolisation and surgical treatment on ovarian function in women with uterine fibroids [PDF]

, 2010
Objective The aim of this study was to evaluate and compare both ovarian function and menstrual characteristics following uterine artery embolisation (UAE) and surgery. Design Subgroup of women from a randomised controlled trial.
D. Lyons, Murray, G. D., S. Rashid, Cooper, K., Rashid, S., Khaund, A., Lumsden, M.A., Moss, J.G., Murray, L.S., Lumsden, M. A., Moss, J. G., J. G. Moss, M. A. Lumsden, Lyons, D., K. Cooper, Murray, G.D., A. Khaund, Murray, L., L. S. Murray, G. D. Murray   +19 more
core   +1 more source