Advanced Biology, EarlyView.The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li +10 more
wiley +1 more source
The value of intraoperative consultation (frozen section) in the diagnosis of ovarian neoplasms [PDF]
, 1998 Alp Usubütün +2 more
openalex +1 more source
The Regulation of Trace Metal Elements in Cancer Ferroptosis
Advanced Biology, EarlyView.The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang +5 more
wiley +1 more source
The Histopathological Patterns of Ovarian Neoplasms in Different Age Groups: A Retrospective Study in a Tertiary Care Center. [PDF]
Cureus, 2022 Farag NH +6 more
europepmc +1 more source
Expression of p53 Protein and Ki-67 Reactivity in Ovarian Neoplasms:Correlation With Histopathology [PDF]
, 1996 A Harłozińska +3 more
openalex +1 more source
Intersection Between Local Anesthetics and Cancer Biology: What Now? Where Are We Going?
Advanced Biology, EarlyView.Local anesthetics (LAs), widely used in anesthesia, may also play a role in cancer treatment by inhibiting tumor growth, reducing metastasis, and enhancing immune responses. They modulate key pathways like AKT/mTOR and RAS/ERK while affecting angiogenesis and tumor innervation and the immune response.
Eduardo Nunez‐Rodriguez +3 more
wiley +1 more source
Educational Case: Ovarian neoplasms: A series of educational cases to review malignancies of epithelial, stromal, and germ cell origin. [PDF]
Acad Pathol, 2023 Tumas JB, Chan J.
europepmc +1 more source
Recent advances in immunohistochemistry in the diagnosis of ovarian neoplasms [PDF]
, 2000 W. Glenn McCluggage
openalex +1 more source
Advanced Functional Materials, EarlyView.This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley +1 more source
A Case Report of Pseudomyxoma Peritonei Arising From Primary Mucinous Ovarian Neoplasms. [PDF]
Cureus, 2022 Joseph R +4 more
europepmc +1 more source